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Latest Cellular differentiation Stories

2013-12-03 13:59:23

The electrophysiological properties of potassium ion channels are regarded as a basic index for determining the functional differentiation of neural stem cells. A recent study published in the Neural Regeneration Research (Vol. 8, No. 28, 2013) showed that the proliferating neural stem cells selected were capable of differentiating into neural cells, and the differentiation process was accompanied by the expression of potassium currents. After 2 weeks of differentiation and development, the...

2013-11-26 16:24:38

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These “daughter” cells must be produced at a rate of about one million per second to constantly replenish the body’s blood supply. Researchers have long wondered what allows these stem cells to persist for decades, when their progeny last for days, weeks or months before they need to...

2013-11-21 13:05:17

Scientists at Karolinska Institutet in Sweden have discovered that two separate species of salamander differ in the way their muscles grow back in lost body parts. Their findings on the species-specific solutions, published in the scientific periodical Cell Stem Cell, demonstrate there is more than one mechanism of tissue regeneration. To carry out their study, the scientists labelled different cell types in two species of salamander in order to ascertain what kinds of cell give rise to...

Scientists Generate 'Mini-kidney' Structures From Human Stem Cells For The First Time
2013-11-18 11:37:04

Salk Institute Findings may lead to much-needed therapies for kidney disease Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology. Now, a team of researchers led by scientists at the Salk Institute for Biological Studies has developed a novel platform to study kidney diseases, opening new avenues...

2013-11-04 09:16:31

Kidney repair may not require stem cells Harvard Stem Cell Institute (HSCI) researchers have a new model for how the kidney repairs itself, a model that adds to a growing body of evidence that mature cells are far more plastic than had previously been imagined. After injury, mature kidney cells dedifferentiate into more primordial versions of themselves, and then differentiate into the cell types needing replacement in the damaged tissue. This finding conflicts with a previously held...

Stem Cells Reveal Differences Humans Apes
2013-10-24 09:27:59

redOrbit Staff & Wire Reports - Your Universe Online For the first time, scientists from the Salk Institute for Biological Studies have taken stem cells from chimpanzees and bonobos and turned them into induced pluripotent stem cells (iPSCs), and their work has helped to highlight some of the differences between humans and non-human primates. This type of cell, which has the ability to form any other type of cell or tissue in the body, can be used to model diseases that would...

2013-10-23 10:21:34

Technique has potential use in regenerative medicine and drug development University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods. "The work allows for a better understanding of how to turn stem cells into clinically useful cell types more...

2013-10-22 12:10:02

In a feat of modern-day alchemy with huge potential for regenerative medicine, Stanford University School of Medicine scientists have developed a fast, efficient way to turn cells extracted from routine liposuction into liver cells. The advance is described in a study to be published Oct. 21 in Cell Transplantation. The scientists performed their experiments in mice, but the adipose stem cells they used came from human liposuction aspirates and became human, liver-like cells that...

Mature Cells Revert Into Embryonic-like Stem Cells With Help From Physical Cues
2013-10-21 09:40:41

University of California - Berkeley Bioengineers at the University of California, Berkeley, have shown that physical cues can replace certain chemicals when nudging mature cells back to a pluripotent stage, capable of becoming any cell type in the body. The researchers grew fibroblasts cells taken from human skin and mouse ears on surfaces with parallel grooves measuring 10 micrometers wide and 3 micrometers high. After two weeks of culture in a special cocktail used to reprogram mature...

2013-10-15 12:52:40

Researchers at the University of Illinois at Chicago have identified a protein expressed by human bone marrow stem cells that guides and stimulates the formation of blood vessels. Their findings, which could help improve the vascularization of engineered tissues, were reported online Oct. 12 in the Journal of Molecular and Cellular Cardiology. “Some stem cells actually have multiple jobs,” says Dr. Jalees Rehman, associate professor of cardiology and pharmacology at the UIC College...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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