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Latest Cellular processes Stories

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2009-06-15 09:55:00

Study shows stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth diseaseStalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology (www.jcb.org). A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.The mutations behind CMT disease slow nerve impulses,...

2009-06-11 14:46:36

 "Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.Autophagy is a process in which cancer cells eat themselves. Previous study from the lab of Eileen White, PhD, associate director for...

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2009-06-12 15:15:00

Those stubborn grey hairs that come with age really are signs of stress, albeit of the cellular kind, according to a new Japanese study. Genotoxic stress, which is anything that damages our DNA, sets off a chain reaction in which specialized cells known as melanocyte stem cells (MSCs) become damaged, ultimately resulting in a malfunction of the cells responsible for hair color. Scientists discovered that the type of genotoxic stress that damages DNA depletes the MSCs in hair follicles that...

2009-05-31 09:18:23

By using ultrafast laser pulses to slice off pieces of chromosomes and observe how the chromosomes behave, biomedical engineers at the University of Michigan have gained pivotal insights into mitosis, the process of cell division. Their findings could help scientists better understand genetic diseases, aging and cancer. Cells in plants, fungi, and animals"”including those in the human body"”divide through mitosis, during which the DNA-containing chromosomes separate between the...

2009-05-25 07:49:55

An emerging form of the pathogenic yeast Candida is able to complete a full sexual cycle in a test tube, even though it's missing the genes for reproduction. And it may also do so while infecting us, according to Duke University Medical Center researchers."Sex contributes to the Candida yeast species' evolutionary success," said Joseph Heitman, M.D., Ph.D., director of the Center for Microbial Pathogenesis in the Duke Department of Molecular Genetics and Microbiology and co-author of two...

2009-05-21 12:53:31

A new study published online in Nature Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at stages that coincide with V(D)J recombination of the heavy and light chain (Igh and Igk) loci. Researchers led by Jane A. Skok Ph.D., assistant professor in the Department of Pathology at NYU School of Medicine and a member of the NYU Cancer Institute, showed that the V(D)J recombinase, which consists of the RAG1 and RAG2...

2009-05-18 02:00:00

Astral Fruit, a new health supplements product, helps slow and repair some of the natural telomere DNA shortening that happens as we age MIAMI, May 18 /PRNewswire/ -- RevGenetics announces the update and release of its latest science-based telomere health supplements, Astral Fruit. To understand what and how Astral Fruit works we can look at a recent study entitled: "Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease."* The August 2008...

2009-02-25 12:06:12

Starting with the tiny fruit fly, and then moving into mouse and human patients, researchers at VIB connected to the Center for Human Genetics (K.U. Leuven) showed that the same gene suppresses cancer in all three. Reciprocally, switching off the gene leads to cancer. The scientists think there is a good chance that the gene can be switched on again with a drug. They report their findings in the reputed scientific journal PLoS Biology.Specialized cellsAll of us begin our lives as one cell,...

2009-02-06 10:03:50

Team finds that Orc1, part of machinery that initiates DNA replication, prevents excess centrosome duplication Before a cell can divide into two, first it must duplicate its genetic material--the DNA packed in its chromosomes. The two new sets of chromosomes then have to be separated from one another and correctly distributed to the resulting "daughter" cells, so that both daughter cells are genetically identical to the original, or "parent," cell. During cell division, a cellular organ...

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2009-01-26 14:12:10

Study uncovers long-sought mechanism that limits centriole duplication, with implications for potential cancer treatments Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' replication. The study will appear in the January 26, 2009 issue of the Journal of Cell Biology. Centrioles start reproducing themselves during...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.