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Last updated on April 18, 2014 at 17:24 EDT

Latest Cellular processes Stories

2013-08-08 15:15:20

Researchers at Warwick Medical School have identified the key role played by a team of proteins in the process of mitosis. Working out how to control them may give scientists a way to destroy cancerous cells. The study, published in The Journal of Cell Biology, highlights the role of a newly identified team of proteins, TACC3-ch-TOG-clathrin, in forming inter-microtubule bridges that stabilize the kinetochore fibers (K-fibers) used in mitosis. When a cell divides, it produces a mitotic...

2013-07-29 16:18:27

A seafood contaminant that thrives in brackish water during the summer works like a spy to infiltrate cells and quickly open communication channels to sicken the host, researchers at UT Southwestern Medical Center report. Vibrio parahaemolyticus bacteria, which cause gastroenteritis, inject proteins called effectors into host cells. One of those effectors, VopQ, almost immediately starts to disrupt the important process of autophagy via a novel channel-forming mechanism, the scientists...

2013-07-23 14:56:51

The duplication of cellular contents and their distribution to two daughter cells during cell division are amongst the most fundamental features of all life on earth. How cell division occurs and is coordinated with organismal development is a subject of intense research interest, as is how this process malfunctions in the development of tumors. Alex Dammermann and his team from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna, together...

2013-07-19 10:56:35

Biologists at the California Institute of Technology (Caltech) have worked out the details of a mechanism that leads undifferentiated blood stem cells to become macrophages—immune cells that attack bacteria and other foreign pathogens. The process involves an unexpected cycle in which cell division slows, leading to an increased accumulation of a particular regulatory protein that in turn slows cell division further. The finding provides new insight into how stem cells are...

2013-07-11 16:34:59

Salk researchers' findings on chromosome shortening suggest a potential target to arrest cancer cell growth A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures...

2013-05-06 20:35:12

The human body contains trillions of cells, all derived from a single cell, or zygote, made by the fusion of an egg and a sperm. That single cell contains all the genetic information needed to develop into a human, and passes identical copies of that information to each new cell as it divides into the many diverse types of cells that make up a complex organism like a human being. If each cell is genetically identical, however, how does it grow to be a skin, blood, nerve, bone or other type...

2013-04-30 13:57:08

NIH-funded study reveals protein, fatty molecules and cellular energy work together during endocytosis Cells ingest proteins and engulf bacteria by a gymnastic, shape-shifting process called endocytosis. Researchers at the National Institutes of Health revealed how a key protein, dynamin, drives the action. Endocytosis lets cells absorb nutrients, import growth factors, prevent infections and accomplish many other vital tasks. Yet, despite decades of research, scientists don't fully...

Researchers Buzzed Over Caffeine As Cancer-cell Killer
2013-04-19 12:13:18

University of Alberta UAlberta research team uses caffeine and fruit flies to pinpoint genetic pathways that guide DNA repair in cancer cells. Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine´s lethal effects on cancer cells–results that could one day be used to advance cancer therapies for people. Previous research has established that caffeine interferes with processes in cancer cells that...

2013-04-09 08:29:31

SAN FRANCISCO, April 9, 2013 /PRNewswire/ -- Cleave Biosciences announced today it has raised $10 million in an extension of its Series A financing from new investor New Enterprise Associates (NEA), bringing its Series A total to $54 million. In the fall of 2011, Cleave raised $44 million from US Venture Partners, 5AM Ventures, Clarus Ventures, OrbiMed Advisors, Astellas Venture Management and Osage University Partners to fund the biopharmaceutical company's cancer drug discovery...

2013-03-18 20:57:34

Results showing the same signaling enzymes can trigger two different processes in the cell sound a warning to biomedical researchers Stroke, heart attacks and numerous other common disorders result in a massive destruction of cells and tissues called necrosis. It´s a violent event: As each cell dies, its membrane ruptures, releasing substances that trigger inflammation, which in turn can cause more cellular necrosis. A new Weizmann Institute study may help develop targeted therapies...