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Latest Cellular processes Stories

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2011-08-18 13:48:11

When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell's interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. The unexpected degree of trial-and-error involved in this process could explain why errors in the number of chromosomes in the egg cell are the leading cause of miscarriages and severe congenital diseases such as trisomies like Down's...

2011-08-08 06:43:56

The human genome is peppered with repeated DNA elements that can vary from a few to thousands of consecutive copies of the same sequence. During meiosis"”the cell division that produces sperm and eggs"”repetitive elements place the genome at risk for dangerous rearrangements from genome reshuffling. This recombination typically does not occur in repetitive DNA, in part because much of it is assembled into specialized heterochromatin. Other mechanisms that restrain recombination in...

2011-08-08 06:34:54

Discovery may have implications for many diseases Cells are the building blocks of the human body. They are a focus of scientific study, because when things go wrong at the cellular and molecular level the consequences for human health are often significant. A new finding based on multiple collaborations between UNC and Duke scientists over several years points to new avenues for investigation of cell metabolism that may provide insights into diseases ranging from neurodegenerative disorders...

2011-07-07 19:23:55

Scripps Research Institute scientists have discovered a basic mechanism that can enable developing cancer cells to sustain abnormal growth. The finding is expected to lead to the targeting of this mechanism with drugs and diagnostic techniques. The study, which recently appeared in the early online edition of the Proceedings of the National Academy of Sciences, illuminates the roles of two nearly identical proteins, Cks1 and Cks2. These proteins were known to be overexpressed in many cancers,...

2011-06-30 19:04:02

Results suggest novel approach to developing targeted cancer therapies Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer"”suggesting the possibility of new therapies that might target the specific changes underlying the disease. The findings will be published online in the journal Cell on June 30, 2011. The process investigated by Alfonso Bellacosa,...

2011-06-22 22:43:37

New studies illuminate brain's complex neurotransmission machinery, point to potential source of problems leading to neurodegenerative and psychiatric conditions Two studies featuring research from Weill Cornell Medical College have uncovered surprising details about the complex process that leads to the flow of neurotransmitters between brain neurons -- a dance of chemical messages so delicate that missteps often lead to neurological dysfunction. A recent Nature Neuroscience study led by Dr....

2011-06-09 23:33:23

Blocking cyclin D1 might help sensitize tumors to radiation Scientists at Dana-Farber Cancer Institute have uncovered a new role for a key cancer protein, a finding that could pave the way for more-effective radiation treatment of a variety of tumors. Many cancers are driven in part by elevated levels of cyclin D1, which allow the cells to escape growth controls and proliferate abnormally. In the new research, reported in the June 9 issue of Nature, researchers discovered that cyclin D1 also...

2011-06-07 22:21:29

Five distinguished Baylor College of Medicine scientists will receive the annual Michael E. DeBakey, M.D., Excellence in Research Awards Tuesday. The scientists will present their research and receive their awards in a special program from 2 to 4 p.m. in Alkek N315. These awards recognize significant and outstanding research accomplishments by scientists at BCM. The recipients present their work during a seminar at which they receive Excellence in Research medallions. The awards also include...

2011-05-31 13:32:58

A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found. The drug, a type of histone deacetylase (HDAC) inhibitor being evaluated in numerous ongoing clinical trials, has been shown to reverse the harmful effects of autophagy in heart muscle cells of mice. Autophagy is a natural process by which cells eat their own proteins to provide needed resources in times of stress. The new...

2011-05-27 19:48:59

Molecular mechanism of selected autophagy elucidated Salmonella is widely prevalent in the animal kingdom. The reason we do not suffer from severe intestinal infections very often is due to our body's defense system, which manages to digest invading bacteria. This is why, generally speaking, a healthy human being will only fall ill if he consumes more than 100.000 salmonella bacteria via a contaminated food source, such as eggs or meat. An international team of researchers, led by Prof. Ivan...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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