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Latest Center for Applied Genomics Stories

2012-12-03 16:11:16

Neuroblastoma patients with ARID1A and ARID1B mutations have more aggressive disease In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who...

2012-12-03 16:07:43

Researchers at The Children's Hospital of Philadelphia part of a large international study An international team of genetics researchers has discovered four new gene regions that contribute to low birth weight. Three of those regions influence adult metabolism, and appear to affect longer-term outcomes such as adult height, risk of type 2 diabetes and adult blood pressure. "This large study adds to the evidence that genes have a strong influence on fetal growth," said one of the...

2012-11-13 12:06:54

New computational analysis identifies gene networks affected in schizophrenia and shows that schizophrenia and autism share related genetic networks, each composed of hundreds of genes Although schizophrenia is highly genetic in origin, the genes involved in the disorder have been difficult to identify. In the past few years, researchers have implicated several genes, but it is unclear how they act to produce the disorder. A new study by researchers at Columbia University Medical Center...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.