Quantcast

Latest Channelrhodopsin Stories

2014-04-25 10:11:04

Leaps orders of magnitude beyond existing tools -- NIH study Scientists have bioengineered, in neurons cultured from rats, an enhancement to a cutting edge technology that provides instant control over brain circuit activity with a flash of light. The research funded by the National Institutes of Health adds the same level of control over turning neurons off that, until now, had been limited to turning them on. "What had been working through a weak pump can now work through a highly...

2014-04-25 10:04:46

Much-needed tool for neuroscience emerges after years of work Nearly a decade ago, the era of optogenetics was ushered in with the development of channelrhodopsins, light-activated ion channels that can, with the flick of a switch, instantaneously turn on neurons in which they are genetically expressed. What has lagged behind, however, is the ability to use light to inactivate neurons with an equal level of reliability and efficiency. Now, Howard Hughes Medical Institute (HHMI) scientists...

2014-04-01 15:11:54

KIT computer models explain how ion channels in cell membranes react to light / light switch for nerve cells as a sensitive tool of research Networked nerve cells are the control center of organisms. In a nematode, 300 nerve cells are sufficient to initiate complex behavior. To understand the properties of the networks, re-searchers switch cells on and off with light and observe the resulting behavior of the organism. In the Science journal, sci-entists now present a protein that...

2013-10-17 17:14:11

A new technique allows researchers to activate proteins in the brain by shining an LED light on them With the flick of a light switch, researchers at the Salk Institute for Biological Studies can change the shape of a protein in the brain of a mouse, turning on the protein at the precise moment they want. This allows the scientists to observe the exact effect of the protein's activation. The new method, described in the October 16 issue of the journal Neuron, relies on specially engineered...

Motivation Pathways In The Brain Can Fail And Cause Depression
2012-11-19 06:37:26

redOrbit Staff & Wire Reports - Your Universe Online Researchers from Stanford University have isolated the neurons responsible for determining whether or not exerting effort in order to complete a task is worth the energy that said effort will require -- a discovery which could help medical professionals better deal with depression and other brain-related disorders. According to the university, many psychiatrists believe that a person's "will to act" originates from the prefrontal...

2011-08-11 06:42:48

(Ivanhoe Newswire) -- A new technique that stimulates heart muscle cells with low-energy light raises the possibility of a future light-controlled pacemaker, according to this study. "Electronic cardiac pacemakers and defibrillators are well established and successful technologies, but they are not without problems, including the breakage of metal leads, limited battery life and interference from strong magnetic fields," Emilia Entcheva, Ph.D., senior author of the study and associate...

2010-01-22 13:39:46

Researchers at the medical university Karolinska Institutet have created a genetically modified mouse in which certain neurons can be activated by blue light. Shining blue light on brainstems or spinal cords isolated from these mice produces walking-like motor activity. The findings, which are published in the scientific journal Nature Neuroscience, are of potential significance to the recovery of walking after spinal cord injury. "This new mouse model will impact the way in which future...

2010-01-07 13:48:04

New tools show potential for treating brain disorders Neuroscientists at MIT have developed a powerful new class of tools to reversibly shut down brain activity using different colors of light. When targeted to specific neurons, these tools could potentially lead to new treatments for the abnormal brain activity associated with disorders such as chronic pain, epilepsy, brain injury, and Parkinson's disease. The tools work on the principle that such disorders might be best treated by...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.