Quantcast

Latest Chaperone Stories

2011-08-24 21:53:33

Evidence found for a neuronal switch to prevent neurodegenerative diseases Scientists at Northwestern University report a surprising discovery that offers a possible new route for the treatment of neurodegenerative diseases. In a study of the transparent roundworm C. elegans, they found that a genetic switch in master neurons inhibits the proper functioning of protective cell stress responses, leading to the accumulation of misfolded and damaged proteins. Neurodegenerative diseases,...

2011-08-23 21:33:41

New Findings Could Have Important Implications for Current Cancer Treatments In a joint research effort with researchers at St. Jude Children´s Research Hospital, and with help from scientists at The University of Pennsylvania, The University of Minnesota, and the National Institutes of Health, investigators from the Florida campus of The Scripps Research Institute have defined a specific protein complex that allows cells to rid themselves of damaged mitochondria, which are the energy...

2011-05-04 08:00:00

CHICAGO, May 4, 2011 /PRNewswire/ -- Media Chaperone, developer of Piggyback - a first of its kind Facebook application that helps parents monitor their kids' online game use - today announced a strategic partnership with Frima Studio, Canada's leading independent game developer. The partnership will provide tens of millions of parents the ability to monitor and reward their children's online gaming activity while playing Frima developed games. (Logo:...

2011-03-15 20:51:32

When vital proteins in our bodies are misfolded, debilitating diseases can result. If researchers could see the folding happen, they might be able to design treatments for some of these diseases or even keep them from occurring. But many of our most critical proteins are folded, hidden from sight, inside tiny molecular chambers. Now researchers at Stanford have gotten the first-ever peek inside one of these protein-folding chambers as the folding happened, and the folding mechanism they saw...

2011-03-07 15:41:41

Parents and their teenagers often have differing opinions when it comes to spring break, especially regarding travel plans and safety. A pediatrician at Baylor College of Medicine offers tips on how parents can decide which situations are best for their teens. "I think a lot of parents and teens feel pressure at spring break time and this can be a difficult topic to tackle when you do not agree," said Dr. Sara Rizvi, assistant professor of pediatrics at BCM and Texas Children's Hospital. "It...

2011-01-21 14:28:57

Acetylation complex fits like a halo over a histone To understand the emerging science of epigenetics"”a field that describes how genes may be regulated without altering the underlying DNA itself"”scientists are deciphering the many ways in which enzymes act on the proteins surrounding DNA within cells. One type of these enzymes, proteins known as histone acetyltransferases (HATs), act on DNA by modifying DNA-bound proteins called histones. This act of modification, called...

2011-01-07 18:47:37

A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety of abnormalities and diseases. Cells don't come prefabricated, with pieces plunked down and tacked together like modular homes offloaded from trucks. The structural proteins that give cells shape, tubulin and actin (think beams and girders), are themselves subject to...

2010-12-08 08:00:00

CRANBURY, N.J., Dec. 8, 2010 /PRNewswire/ -- Amicus Therapeutics (Nasdaq: FOLD), a biopharmaceutical company focused on developing treatments for rare diseases, today announced that it has been awarded a second grant from The Michael J. Fox Foundation for Parkinson's Research (MJFF) for the development of a novel, next-generation pharmacological chaperone for the treatment of Parkinson's disease. The $500,000 award will be distributed over a period of 24 months. Amicus' studies will be...

2010-10-28 23:03:53

Mad Cow disease and its human variant Creutzfeldt"”Jakob disease, which are incurable and fatal, have been on a welcome hiatus from the news for years, but because mammals remain as vulnerable as ever to infectious diseases caused by enigmatic proteins called prions, scientists have taken no respite of their own. In the Oct. 29 edition of the journal Science, researchers at Brown University report a key new insight into how prion proteins "” the infectious agents "” become...

2010-06-18 01:55:35

Physicists at UC Santa Barbara have created a microscopic device to assist biologists in making very fast molecular measurements that aid the understanding of protein folding. This development may help elucidate biological processes associated with diseases such as Alzheimer's and Parkinson's. Since proteins in the body perform different functions according to their shape, the folding process is considered a key area of study. Using a microfabricated fluid mixing device built at UCSB's...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
Related