Quantcast

Latest CHEK1 Stories

2012-03-14 09:37:26

The authors, from Oscar Fernandez Capetillo's group, have identified this double-edged property in the gene Chk1, an established tumor suppressor Can a gene simultaneously protect against cancer and favor its growth? Researchers at the Spanish National Cancer Research Centre have discovered a gene with this double-edged property and suspect there may be many more that share it. In the words of Oscar Fernandez Capetillo, head of the group responsible for the study, this gene "can be both...

2012-01-03 14:51:00

Scientists have found at least one instance when the smaller sibling gets to call the shots and cancer patients may one day benefit. The protein Chk1 has long been known to be a checkpoint in cell development: it keeps normal cells and damaged cells from dividing until their DNA has been fully replicated or repaired. Now scientists at Georgia Health Sciences University and the California Institute of Technology have discovered a shorter form they've dubbed Chk1-S ("S" stands for short)...

2009-09-01 07:24:01

Cell cycle checkpoints act like molecular tripwires for damaged cells. Leave the tripwire in place for too long, however, and cancer cells will press on regardless, making them resistant to certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies. "A lot of progress has been made in understanding the molecular details of checkpoint activation," senior author Tony Hunter, Ph.D., a professor in the Molecular and Cell Biology Laboratory was quoted as...

2005-09-02 16:07:00

(September 2, 2005, La Jolla, CA) "“ A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs. The study is expected to help academic researchers and biotechnology and pharmaceutical...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'