Latest chemical library Stories
CLEVELAND, Oct. 15, 2012 /PRNewswire/ -- ChanTest, the industry leading ion channel Contract Research Organization (CRO) announces today the addition of a 50,000 compound chemical library from Enamine Ltd., a leading provider of screening compounds and chemical building blocks. This compound library (3D Diversity Set) will be available to ChanTest clients effective immediately as a key tool for drug discovery services. (Logo: http://photos.prnewswire.com/prnh/20120817/CL58977LOGO...
By Kim McDonald, UC San DiegoUsing an automated screening technique developed by pharmaceutical companies to find new drugs, a team of researchers from UC San Diego and three other research institutions has discovered a molecule with the most potent effects ever seen on the biological clock.Dubbed by the scientists "longdaysin," for its ability to dramatically slow down the biological clock, the new compound and the application of their screening method to the discovery of other...
The identification of compounds that could be promising candidates for drug development has become easier following research by the Walter and Eliza Hall Institute's medicinal chemistry group.Dr Jonathan Baell and Dr Georgina Holloway have developed a series of 'filters' that can be used to weed out those molecules likely to come up as false positives when screening a chemical library for compounds that could be useful in drug development.High-throughput chemical screening (HTCS) seeks to...
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through"”time and money make it virtually impossible to screen or search through super-large libraries of potential compounds. This is a serious problem, because there is enormous interest in identifying synthetic molecules that bind to proteins for applications in drug discovery, biology, and proteomics, and larger...
Cancer and cell biology experts at the University of Cincinnati (UC) have developed a new mass spectrometry-based tool they say provides more precise, cost-effective data collection for drug discovery efforts.Preliminary studies have shown that the new mass spectrometry tool"”known as MALDI-QqQMS (matrix-assisted laser desorption ionization-triple quadruple mass spectrometer)"”provides a superior means of measuring the enzyme reactions critical to drug discovery at speeds comparable to...
