Quantcast
Last updated on April 17, 2014 at 11:49 EDT

Latest Chemokine Stories

2014-04-17 09:48:21

Findings may advance efforts to better manage the infection A team of scientists led by Johns Hopkins and Stanford University researchers has laid the groundwork for understanding how variations in immune responses to Lyme disease can contribute to the many different outcomes of this bacterial infection seen in individual patients. A report on the work appears online April 16 in PLOS One. "Physicians have recognized for many years that Lyme disease is not a uniform disease process and...

2013-10-30 00:21:41

TAIPEI, Oct. 29, 2013 /PRNewswire/ -- TaiGen Biotechnology Company, Limited ("TaiGen") announced the results from the US Phase IIa trial of TG-0054, a CXC chemokine receptor 4 (CXCR4) antagonist, in stem cell transplantation will be presented in an Oral Session at the 55th ASH Annual Meeting and Exposition (December 7-10, 2013) in New Orleans, LA, U.S.A. Presentation details: Title: Rapid Mobilization Of CD34+ Stem Cells With TG-0054, a Novel CXC Chemokine Receptor 4 (CXCR4)...

2013-09-26 17:57:27

Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively erasing the path behind them. The findings, published online today in Nature, could have implications not just for development but also for cancer and metastasis. As a zebrafish embryo develops, a...

2013-04-03 16:25:00

NORCROSS, Ga., April 3, 2013 /PRNewswire/ -- RayBiotech, Inc. announced today that the application of its Mouse Cytokine Antibody Array has enabled the identification of key factors involved in the dissemination of leprosy infection in humans. This seminal research was conducted by Dr. Anura Rambukkana and colleagues at the Medical Research Council Center for Regenerative Medicine, University of Edinburgh and the Rockefeller University in New York. In this study, Dr. Rambukkana's team...

2013-02-19 15:01:49

LMU researchers led by Christian Weber have, for the first time, elucidated how cells that promote the development of atherosclerosis find their way to the blood vessel wall, where they stimulate the formation of obstructive deposits. Atherosclerosis is one of the commonest causes of death in modern societies. The condition is characterized by the build-up of fatty deposits called atherosclerotic plaques on the inner surfaces of arteries, which restrict, and may eventually cut off, blood...

2012-12-28 15:28:26

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition. “Clinically, scientists have focused on trying to understand how cartilage and joints degenerate in osteoarthritis. But no one knows why it hurts,” said Dr. Anne-Marie...

2012-10-24 15:26:13

SAVAGE, Md., Oct. 24, 2012 /PRNewswire/ -- Chesapeake PERL has received a Small Business Innovation Research award from the National Cancer Institute to continue development of a protein nanoparticle linked to an antitumor agent as a potential lung cancer therapeutic. C-PERL collaborators in the laboratory of Dr. Leonard Rome, Professor of Biological Chemistry at UCLA have identified and characterized the vault particle, a unique nanoparticle structure ubiquitous in eukaryotes. Starting...

How Metastasizing Cancer Cells Can Enter Organs
2012-07-11 18:38:46

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies. Every year, over seven million people die of cancer worldwide. Thanks to...

How Do Tumor Cells Create Their Own Pathways
2012-07-10 15:34:19

Potential new treatment for metastatic colon cancer How does a tumor cell set up a signaling pathway in order to metastasize? Scientists at Technische Universität München's (TUM) Klinikum rechts der Isar and Helmholtz Zentrum München have made a significant discovery in this area by studying colon cancer. They have learned that the tumor cells release certain proteins known as chemokines. In the case of metastatic colon cancer cells, the...

2012-06-07 08:49:08

Study finds that HIV receptor CCR5 is induced by oncogenes in breast cancer cells, too The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue of Cancer Research. Such drugs target the HIV receptor CCR5, which the virus uses to enter and infect host cells, and has historically only been associated with expression in...