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Latest Chloroquine Stories

2013-03-21 16:13:24

Drug may be major advance as malaria has developed resistance to existing treatments Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and preventing malaria – a disease that kills more than one million people each year. The scientists have described the drug, and its effectiveness against mice infected with malaria, in the March 20 issue of Science...

2012-10-03 14:55:41

Malaria-drug monitoring over the past 30 years has shown that malaria parasites develop resistance to medicine, and the first signs of resistance to the newest drugs have just been observed. At the same time, resistance monitoring at the University of Copenhagen shows that the previously efficacious drug chloroquine is once again beginning to work against malaria. In time that will ensure cheaper treatment for the world´s poor. Scientists and healthcare personnel the world over fear...

2012-08-23 00:55:46

Medicines for Malaria Venture has developed a framework to evaluate the risk of resistance for the antimalarial compounds in its portfolio. A paper based on this work: A framework for assessing the risk of resistance for antimalarials in development has been published in the Malaria Journal today. Resistance defines the longevity of every anti-infective drug, so it is important when developing new medicines for malaria, to check how easily promising antimalarial compounds will select for...

2012-07-04 22:53:53

In most comprehensive review of a decade of data researchers confirm indoor insecticide treatments, dramatically reduce malaria; study finds world´s best drug still effective in African malaria 'hot zone' while researchers question for how long A pair of provocative studies in the July 2012 issue of The American Journal of Tropical Medicine and Hygiene (AJTMH) provides a window into the intense ground war now underway against malaria. In one review, researchers offer new evidence...

2012-04-05 21:19:01

Genetics study identifies key genome region underlying artemisinin resistance in malaria parasite Evidence that the most deadly species of malaria parasite, Plasmodium falciparum, is becoming resistant to the front line treatment for malaria on the border of Thailand and Myanmar (Burma) is reported in The Lancet today. This increases concern that resistance could now spread to India and then Africa as resistance to other antimalarial drugs has done before. Eliminating malaria might then...

2012-04-05 21:17:39

Emergence of resistance to the drug artemisinin in western Thailand has created a critical point in global efforts to control and eliminate malaria worldwide, according to a new study published in the Lancet, a British Medical Journal, by researchers at the Texas Biomedical Research Institute and their collaborators in Thailand. A second study, published concurrently in the journal Science by the same research groups, identifies a major region of the malaria parasite genome associated with...

2011-12-08 10:26:42

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans — by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers. The study, published in the November 11, 2011 issue of PLoS ONE, was...

2011-08-05 12:06:01

Possible resistance-proof drug pairs found by NIH scientists Numerous potential anti-malarial candidate drugs have been uncovered by investigators from the National Institute of Allergy and Infectious Diseases (NIAID) and the National Human Genome Research Institute (NHGRI), both parts of the National Institutes of Health (NIH). Researchers at the NIH Chemical Genomics Center, administered by NHGRI, used robotic, ultra-high-throughput screening technology to test more than 2,800 chemical...

2011-07-18 15:08:00

GRAND RAPIDS, Mich., July 18, 2011 /PRNewswire/ -- In a study published recently in the journal Science Signaling Van Andel Research Institute (VARI) scientists demonstrate on the molecular level how the anti-malaria drug chloroquine represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis, and certain cancers. "The implications of this study are significant," said Henry...

2011-07-18 16:13:53

Anti-malaria drug provides key insight into potential treatments for autoimmune diseases In a study published recently in the journal Science Signaling Van Andel Research Institute (VARI) scientists demonstrate on the molecular level how the anti-malaria drug chloroquine represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis, and certain cancers. Chloroquine is a widely...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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