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Latest Cholangiocarcinoma Stories

2010-02-18 09:00:22

Expression of aldehyde dehydrogenase (ALDH) in pancreatic adenocarcinoma is associated with worse overall survival in patients who have undergone resection for early-stage disease, according to a new study published online February 17 in the Journal of the National Cancer Institute. ALDH activity characterizes normal stem cells and cancer stem cells (CSCs) in several human malignancies, including pancreatic adenocarcinoma; however, the clinical significance of ALDH-expressing cancer stem...

2010-01-15 18:00:46

Incidence of intrahepatic cholangiocarcinoma (ICC) is increasing worldwide and its prognosis is very poor. Thus, further studies on its clinical characteristics for early detection and on surgical treatment for better prognosis are urgently needed. A research team from China retrospectively evaluated 5311 liver cancer patients who received resection between October 1999 and December 2003. Of these, 429 (8.1%) patients were diagnosed with ICC, and their clinicopathological, surgical, and...

2009-12-22 13:41:40

In the field of hepatic imaging in the context of living liver donors and before complex partial liver resections, three-dimensional imaging of the liver, hepatic vessels and bile ducts has managed to become established in some centers. In this case, in addition to visualization, the volumetry of various liver sections is of interest. Moreover, the three-dimensional reconstruction can be used preoperatively to consider various resection options and to evaluate their technical feasibility with...

2009-11-18 14:59:47

Biliary drainage is performed as a palliative treatment of hilar cholangiocarcinoma. The reduction of serum bilirubin is usually the hallmark of successful biliary drainage. However, some patients may have persistent jaundice or scanty bile output after biliary drainage. A research team, led by Dr. Chiung-Yu Chen from National Cheng Kung University retrospectively analyzed the clinical and imaging characteristics of these patients in an attempt to identify the factors related to bile output...

2009-10-09 13:31:31

Scientists have found that the human liver fluke (Opisthorchis viverrini) contributes to the development of bile duct (liver) cancer by secreting granulin, a growth hormone that is known to cause uncontrolled growth of cells. Details are published October 9 in the open-access journal PLoS Pathogens. Drs Michael Smout and Alex Loukas from the Queensland Institute of Medical Research, with collaborators at Khon Kaen University and George Washington University, say they are excited by the novel...

2009-08-28 11:06:50

 A national team of researchers led by scientists at Mayo Clinic has found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients, according to a study published this month in the journal Hepatology.Primary sclerosing cholangitis (PSC) is a disease of the bile ducts. In this case, the term "cholangitis" refers to inflammation of the bile ducts, while "sclerosing" describes the hardening and scarring of the bile ducts that result...

2009-08-20 07:00:00

WOONSOCKET, R.I., Aug. 20 /PRNewswire-FirstCall/ -- MultiCell Technologies, Inc. (OTC Bulletin Board: MCET) announced today it has been granted U.S. patent 7,566,567 by the United States of America Patent and Trademark Office covering its Fa2N-4 and Ea1C-35 immortalized human hepatocyte cell lines. The Fa2N-4 and Ea1C-35 immortalized human hepatocyte cell lines were derived from normal human liver cells, and are nontumorigenic, stable in culture, and produce therapeutic plasma proteins in...

2009-08-19 09:50:00

High-dose ursodeoxycholic acid associated with worsened disease state for patients with PSCPrimary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period. PSC is a common cause of adult cholestatic liver diseases and a primary source behind many of the liver transplantations...

2009-08-06 10:28:35

A research article to be published on August 7, 2009 in the World Journal of Gastroenterology addresses this question. In the present study, 101 consecutive patients with bilateral intrahepatic stones who underwent bilateral liver resection in the past 10 years were reviewed retrospectively. This study demonstrated that bilateral liver resection for bilateral intrahepatic stones was safe, with zero surgical mortality and an acceptable level of postoperative morbidity (28.7%).Its the long-term...

2009-07-16 16:42:57

Survival rate racial differences for gastrointestinal tumors are narrowing between African-Americans and whites, U.S. researchers said. The study, published in the Journal of the American College of Surgeons, found in the case of a rare cancer that begins in the wall of the gastrointestinal tract known as a gastrointestinal stromal tumor, the 30-day surgical mortality rate which was higher in African-Americans prior to the year 2000 has become equivalent in the last 10 years. Over the last...


Latest Cholangiocarcinoma Reference Libraries

Chinese Liver Fluke, Clonorchis sinensis
2014-01-12 00:00:00

The Chinese liver fluke (Clonorchis sinensis) is a species of parasitic worm that is classified within the Platyhelminthes phylum. It can be found in Southeast Asia, Taiwan, Japan, and China and is present in nearly 30,000,000 humans today. It is thought to be one of the world’s most pervading parasites. The Chinese liver fluke requires two intermediate, or secondary, hosts and one definitive, or main, host to successfully complete its lifecycle. The first intermediate host is typically...

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Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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