Latest Cholesterol Stories

The search for rare gene variants associated with heart, lung and blood-related disease traits, as well as those of public health importance found that 1.1 million of the 1.2 million such variants within exomes occur very infrequently, said a Baylor College of Medicine expert in the analysis of such findings in a plenary abstract session at the annual meeting of the American Society of Human Genetics (exomes are the part of the genome that contain protein-coding genes.) "They were often...

BOSTON, Nov. 7, 2012 /PRNewswire/ -- ARI-3037MO was well tolerated in single and repeat ascending dose trials in healthy volunteers ARI-3037MO did not provoke flushing or any other treatment-related adverse effects in 58 healthy male and female volunteers ARI-3037MO was well absorbed orally and plasma levels demonstrated good dose proportionality ARI-3037MO showed encouraging lipid changes in both clinical trials in healthy subjects Arisaph Pharmaceuticals, Inc. announced today...

April Flowers for redOrbit.com - Your Universe Online Statins are the first line of defense for many people with high cholesterol. For some patients, however, statins do not reduce their low-density lipoprotein cholesterol (LDL) levels. LDL is considered the "bad cholesterol." Some patients' bodies are unable to tolerate statins, or they simply do not respond sufficiently to the medication. New research from Brigham and Women's Hospital, presented at the 2012 American Heart Association...

Alan McStravick for redOrbit.com – Your Universe Online As someone who has been taking a daily regimen of probiotics for some time now, a recent study was of particular interest to me. Probiotics, for those of you who don’t already know, are live microorganisms that are found to benefit the microbiome in your stomach and intestinal tract. They are believed to have a beneficial effect on your digestive system and can usually be ingested by enjoying a delicious yogurt or by taking a...

THOUSAND OAKS, Calif., Nov. 6, 2012 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that results from the LAPLACE-TIMI 57 and MENDEL Phase 2 studies evaluating AMG 145 in hypercholesterolemic patients with or without statins, respectively, showed that treatment with AMG 145 resulted in a statistically significant reduction in low-density lipoprotein (LDL) cholesterol. The two studies were presented today at the American Heart Association Scientific Sessions 2012 and...

Connie K. Ho for redOrbit.com – Your Universe Online At the American Heart Association’s Scientific Sessions 2012, researchers recently revealed that genetically engineered tomato plants were able to create a peptide, a string of amino acids, that works similarly to good cholesterol when it is consumed. In the study, mice that consumed modified, freeze-dried, ground tomatoes showed signs of less inflammation and had a decreased amount of plaque build-up in the arteries (otherwise...

LOS ANGELES, Nov. 5, 2012 /PRNewswire/ -- Micropharma Limited today announced plans to launch Cardioviva(TM) (Lactobacillus reuteri NCIMB 30242), the world's only probiotic shown to naturally help reduce LDL-cholesterol, a risk factor for heart disease, by 11.6 percent in hypercholesterolemic adults. Micropharma will launch Cardioviva(TM) in Canada and in the U.S. in early 2013. The announcement was made after an American Heart Association (AHA) Scientific Sessions press...

LOS ANGELES, Nov. 5, 2012 /PRNewswire/ -- Infusions of a novel formulation of apolipoprotein A-I (apoA-I) - the main component of high-density lipoprotein (HDL) - rapidly increased the presence of key biomarkers associated with reverse cholesterol transport, a process by which cholesterol is removed from arteries and transported to the liver for clearance, according to data from a Phase 1 study sponsored by CSL Limited. Rapid removal of cholesterol following a heart attack may play...

LOS ANGELES, Nov. 5, 2012 /PRNewswire/ -- Results from the USAGE survey, the largest known cholesterol survey in the U.S. involving more than 10,100 statin users(1), were presented today at the American Heart Association's Annual Scientific Sessions, the leading gathering of cardiovascular disease experts in the country. John O'Hurley, Seinfeld and Dancing with the Stars actor and high cholesterol patient, is dedicated to educational efforts in support of the USAGE survey. As a...

PRINCETON, N.J., Nov. 5, 2012 /PRNewswire/ -- Omthera Pharmaceuticals, Inc., a privately held specialty pharmaceuticals company, today announced that Phase 3 results from its EVOLVE (EpanoVa fOr Lowering Very High triglyceridEs) and ESPRIT (Epanova combined with a Statin in Patients with HypertRiglycerIdemia to Reduce Non-HDL CholesTerol) clinical trials for Epanova(TM) met all primary and secondary endpoints. The full results from this more than 1,000 patient, global Phase 3...