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Latest Cholinergic anti-inflammatory pathway Stories

2011-09-16 11:35:55

Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science. "The discovery that 2 percent of T cells can make acetylcholine under the...

2010-07-23 02:40:41

Scientists at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have constructed a mathematical and computational model of inflammatory bowel disease that allows researchers to simulate the cellular and molecular changes underlying chronic inflammation in humans. The model allows scientists to explore different interactions of cells in the immune system, check how these cells are linked to inflammation in the colon, and identify intervention points to perhaps stop the disease in...

2009-08-04 13:45:00

OSCEOLA, Wis., Aug. 4 /PRNewswire/ -- NeuroScience, Inc. has launched a new product -- Avipaxin -- aimed at decreasing elevated levels of pro-inflammatory cytokines. Avipaxin supports acetylcholine levels by providing substrates for its production and by inhibiting its metabolizing enzyme, acetylcholinesterase. Initial studies at NeuroScience, Inc. revealed a significant decrease in pro-inflammatory cytokines and chemokines after Avipaxin use. These studies also revealed a decrease in the...

2009-05-06 12:19:19

British scientists say they've determined nicotine can delay the effects of ricin used during a bioterrorism attack. Jon Mabley and his colleagues at the University of Brighton found nicotine works to block the tissue-destroying effects of ricin -- a highly toxic compound derived from castor beans. The study was conducted in laboratory models, but the scientists said nicotine agonists could potentially be used in patients exposed to ricin as a stopgap measure before other treatments take...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'