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Latest Chromosome 21 Stories

2014-04-21 13:46:28

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions. In a study posted online today by the journal Nature Genetics, the researchers track the genetic chain of events that links a chromosomal abnormality in Down syndrome to the cellular havoc...

2013-10-23 11:27:14

Genome-wide changes result from silencing extra chromosome, scientists report at ASHG 2013 The first evidence that the underlying genetic defect responsible for trisomy 21, also known as Down syndrome, can be suppressed in laboratory cultures of patient-derived stem cells was presented today (Oct. 22) at the American Society of Human Genetics 2013 annual meeting in Boston. People with Down syndrome are born with an extra chromosome 21, which results in a variety of physical and...

Down's Syndrome Genes Shut Off In New Breakthrough
2013-07-18 05:30:06

Susan Bowen for redOrbit.com - Your Universe Online Scientists at the University of Massachusetts Medical School have made a huge breakthrough in our understanding of Down's syndrome. They reported in the online science journal Nature, that in a lab, they have switched off the extra chromosome that causes the disorder in humans. This is the proof-of-principal that opens the doorway for exciting new discoveries about this condition. Down's syndrome is the world's leading genetically...

Down Syndrome Researchers Remove Extra Chromosome
2012-11-12 14:52:09

Brett Smith for redOrbit.com - Your Universe Online Geneticists from the University of Washington won a key victory in the battle against genetic diseases by successfully removing the extra chromosome 21 from cells derived from a person with Down syndrome, according to the team´s report in the journal Cell Stem Cell. Down syndrome, also known as trisomy 21, is caused by an extra copy of chromosome 21. In addition to the tell-tale facial features such as an abnormally small chin and...

2012-01-23 21:58:16

Chromosome aberrations happen in pairs when it comes to cancer, TAU research finds A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure – such as an extra copy of a single chromosome – can lead to severe physical impairment. So it's no surprise that when it comes to cancer, chromosomal structure is frequently a contributing factor, says Prof. Ron Shamir of the Blavatnik School of Computer Science at Tel Aviv University. Now...

Flies And Mice Help Scientists Get To The Heart Of Down Syndrome
2011-11-04 10:19:17

[ Watch the Video ] A novel study involving fruit flies and mice has allowed biologists to identify two critical genes responsible for congenital heart defects in individuals with Down syndrome, a major cause of infant mortality and death in people born with this genetic disorder. In a paper published in the November 3 issue of the open access journal PLoS Genetics, researchers from UC San Diego, the Sanford-Burnham Medical Research Institute in La Jolla, Calif., and the University of...

2011-05-02 19:38:29

A protein associated with Alzheimer's disease clogs several motors of the cell transport machinery critical for normal cell division, leading to defective neurons that may contribute to the memory-robbing disease, University of South Florida researchers report. In a new study published online in the journal Cell Cycle, scientists at the USF Health Byrd Alzheimer's Institute. the Florida Alzheimer's Disease Research Center, and Indiana University also suggest that the protein beta amyloid...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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