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Latest Ciliary neurotrophic factor Stories

2012-10-30 12:35:05

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases. In Lou Gehrig's Disease (ALS) and other neurodegenerative diseases, nerve cells usually die in stages, with axons deteriorating first and the cells themselves perishing later. Axon degeneration may represent a...

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2009-12-10 08:35:00

Mouse study suggests that response to injury-induced growth factors can be revived Brain and spinal-cord injuries typically leave people with permanent impairment because the injured nerve fibers (axons) cannot regrow. A study from Children's Hospital Boston, published in the December 10 issue of the journal Neuron, shows that axons can regenerate vigorously in a mouse model when a gene that suppresses natural growth factors is deleted. Adding to a previous study published in Science last...

2009-05-28 07:32:00

LINCOLN, R.I., May 28 /PRNewswire/ -- Neurotech Pharmaceuticals, Inc. today announced that the Company's product candidate, NT-501, demonstrated a strong biologic effect in two Phase 2 clinical trials for retinitis pigmentosa (RP). RP is a slowly developing condition that causes the progressive degeneration of rod & cone photoreceptor cells in the retina that over time diminishes night and peripheral vision and eventually leads to blindness. RP is an orphan-designated indication for which...

2006-02-27 23:05:15

NEW YORK (Reuters Health) - An intraocular implant containing a protein called CNTF, which has been shown to slow retinal degeneration in animals, may improve vision in patients with retinal disease, findings from a study suggest. A variety of genetic mechanisms underlie degenerative retinal diseases, but regardless of the cause the end result is the death of photoreceptor cells. This observation has led researchers to look for therapeutic modalities that would work against these...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.