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Latest Circulating Tumor Cell Stories

2010-12-01 22:00:47

Noncancerous cells from primary site appear to facilitate tumor growth The process of metastasis requires that cancer cells traveling from a primary tumor find a hospitable environment in which to implant themselves and grow. A new study from Massachusetts General Hospital (MGH) Cancer Center researchers finds that circulating tumor cells prepare this environment by bringing along from their original site noncancerous cells that support tumor growth. The report has been published online in...

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2010-10-13 08:20:00

Redesigned microchip-based device provides more data, finds previously unseen CTC clusters A redesigned version of the CTC-Chip "“ a microchip-based device for capturing rare circulating tumor cells (CTCs) "“ appears to be more effective and should be easier to manufacture than the original. Called the HB-(herringbone) Chip, the new device also may provide more comprehensive and easily accessible data from captured tumor cells. Massachusetts General Hospital (MGH) researchers...

2010-10-08 07:00:00

HAYWARD, Calif., Oct. 8 /PRNewswire/ -- Advanced Cell Diagnostics, Inc. (ACD) was awarded a three-year, $3 million grant from National Cancer Institute (NCI) under its SBIR Phase II Bridge Award. This grant will support ACD's continuing effort to develop its proprietary CTCscope(TM) system capable of automatic detection and molecular characterization of circulating tumor cells (CTCs). CTCs are the rare tumor cells detached from solid tumors and circulating in cancer patients' blood. "We...

2010-09-30 09:14:20

(Ivanhoe Newswire) -- Scientists can now learn how drugs work in clinical trials thanks to an innovative technological advance that makes nanoscale protein measurements. "We are making progress toward the goal of understanding how drugs work in different individuals," which Alice C. Fan, M.D., instructor in the division of oncology at Stanford University School of Medicine, was quoted as saying. "Using new technologies makes it possible to measure effects of therapeutic agents in tumor cells...

2010-09-30 09:13:27

(Ivanhoe Newswire) "“ Circulating tumor cells may create a new alternative and non-invasive source for biomarker assessment a new study shows. According to the National Cancer Institute, the major cause of mortality in patients with cancer is caused by tumor cells that escape from the primary tumor into the bloodstream and travel through the circulation to distant sites where they develop into secondary tumors. These are called circulating tumor cells or CTC, and they provide a link...

2010-09-29 12:33:01

A novel technology can make nanoscale protein measurements, which scientists can use in clinical trials to learn how drugs work. "We are making progress toward the goal of understanding how drugs work in different individuals," said Alice C. Fan, M.D., instructor in the division of oncology at Stanford University School of Medicine. "Using new technologies makes it possible to measure effects of therapeutic agents in tumor cells and different cell populations within our patients. Now that we...

2010-09-28 20:53:42

A new disposable device based on advances in microfluidics may help identify advanced breast cancer patients who are candidates for therapy with the drug trastuzumab (Herceptin). The device is described in the American Institute of Physics' journal Biomicrofluidics. Aggressive breast cancers with poor prognosis typically have abnormal levels of the protein HER2 (the tyrosine kinase human epidermal growth factor receptor 2). The new elastomeric, rubber-like device is designed to efficiently...

2010-09-28 20:19:52

Circulating tumor cells (CTCs) may be a promising alternative, noninvasive source of tumor materials for biomarker assessment, according to data presented at the Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development. "The basic idea is that CTCs can provide real-time information about a patient's current disease state, acting as a 'liquid biopsy,'" said Siminder Kaur Atwal, Ph.D., senior research associate at Genentech. "They are much less invasive...

2010-06-07 08:00:00

Results Presented at ASCO 2010 Annual Meeting Confirm Acceptable Safety Profile and Evidence of Biological Activity Including Declines in Circulating Tumor Cells and Reductions in Tumor Markers BOTHELL, WA, and VANCOUVER, June 7 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) today announced final results from a Phase 1 trial. The primary purpose of this trial was to evaluate the safety and tolerability of OGX-427 up to doses of 1000 mg for the treatment of various...

2010-05-28 18:08:32

Researchers uncover that some circulating tumor cells may be worse than others Fox Chase Cancer Center investigators find that pancreatic cancer patients who have circulating tumor cells tend to have worse outcomes than patients without circulating tumor cells. Additionally, the team has uncovered evidence that not all circulating tumor cells are the same, and some may predict worse outcomes than others. Benjamin P. Negin, M.D., a medical oncology fellow at Fox Chase, will present the study...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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