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Latest Circulating Tumor Cell Stories

2012-11-12 12:31:52

System combining nanotechnology and NMR detects particles shed by brain tumors in bloodstream A novel miniature diagnostic platform using nuclear magnetic resonance (NMR) technology is capable of detecting minuscule cell particles known as microvesicles in a drop of blood. Microvesicles shed by cancer cells are even more numerous than those released by normal cells, so detecting them could prove a simple means for diagnosing cancer. In a study published in Nature Medicine, investigators at...

2012-07-06 10:16:15

The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments. Circulating cancer tumor cells are a perfect example. Typically, there are only a handful of them among a billion healthy cells, yet they are precursors to metastasis, the spread of cancer that causes about 90 percent of cancer mortalities. Such "rogue" cells are not limited to cancer...

2012-07-02 13:46:08

Analyzing circulating tumor cells reveals signaling pathway that may be essential to spread of deadly tumor Detailed analysis of genes expressed in circulating tumor cells (CTCs) -- cells that break off from solid tumors and travel through the bloodstream -- has identified a potential treatment target in metastatic pancreatic cancer. In a report that will appear in Nature and has received advance online publication, Massachusetts General Hospital (MGH) Cancer Center investigators describe...

Cancer Cells Could Be Sorted Using Tiny 'Speed Bump' Device
2012-06-12 15:38:13

In life, we sort soiled laundry from clean; ripe fruit from rotten. Two Johns Hopkins engineers say they have found an easy way to use gravity or simple forces to similarly sort microscopic particles and bits of biological matter -- including circulating tumor cells. In the May 25 online issue of Physical Review Letters, German Drazer, an assistant professor of chemical and biomolecular engineering, and his doctoral student, Jorge A. Bernate, reported that they have developed a lab-on-chip...

2012-05-08 09:43:38

The cells that slough off from a cancerous tumor into the bloodstream are a genetically diverse bunch, Stanford University School of Medicine researchers have found. Some have genes turned on that give them the potential to lodge themselves in new places, helping a cancer spread between organs. Others have completely different patterns of gene expression and might be more benign, or less likely to survive in a new tissue. Some cells may even express genes that could predict their response to...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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