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Latest Circulating Tumor Cell Stories

2012-07-06 10:16:15

The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments. Circulating cancer tumor cells are a perfect example. Typically, there are only a handful of them among a billion healthy cells, yet they are precursors to metastasis, the spread of cancer that causes about 90 percent of cancer mortalities. Such "rogue" cells are not limited to cancer...

2012-07-02 13:46:08

Analyzing circulating tumor cells reveals signaling pathway that may be essential to spread of deadly tumor Detailed analysis of genes expressed in circulating tumor cells (CTCs) -- cells that break off from solid tumors and travel through the bloodstream -- has identified a potential treatment target in metastatic pancreatic cancer. In a report that will appear in Nature and has received advance online publication, Massachusetts General Hospital (MGH) Cancer Center investigators describe...

Cancer Cells Could Be Sorted Using Tiny 'Speed Bump' Device
2012-06-12 15:38:13

In life, we sort soiled laundry from clean; ripe fruit from rotten. Two Johns Hopkins engineers say they have found an easy way to use gravity or simple forces to similarly sort microscopic particles and bits of biological matter -- including circulating tumor cells. In the May 25 online issue of Physical Review Letters, German Drazer, an assistant professor of chemical and biomolecular engineering, and his doctoral student, Jorge A. Bernate, reported that they have developed a lab-on-chip...

2012-05-08 09:43:38

The cells that slough off from a cancerous tumor into the bloodstream are a genetically diverse bunch, Stanford University School of Medicine researchers have found. Some have genes turned on that give them the potential to lodge themselves in new places, helping a cancer spread between organs. Others have completely different patterns of gene expression and might be more benign, or less likely to survive in a new tissue. Some cells may even express genes that could predict their response to...

New Microdevice Enables Culture Of Rare Circulating Tumor Cells From Blood
2012-04-24 13:31:25

Ability to culture rare tumor cells isolated from blood could help improve patient response to therapy A research collaboration between the Wyss Institute for Biologically Inspired Engineering at Harvard University and Children´s Hospital Boston has created a microfluidic device that can harvest rare circulating tumor cells (CTCs) from blood to enable their expansion in culture for analysis. These cells, which have detached from a primary cancer site and often create a secondary --...

2012-03-26 13:24:56

Scientists are enlisting the living, self-propelled microbes found in pond scum – the pea-green surface slicks that form on ponds – in the development of a long-awaited new test to detect the cells that spread cancer through the bloodstream from the original tumor to new sites in the body. In a report here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society, they described how the test is intended...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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