Quantcast
Last updated on April 20, 2014 at 5:20 EDT

Latest Circulating Tumor Cell Stories

2010-09-30 09:13:27

(Ivanhoe Newswire) "“ Circulating tumor cells may create a new alternative and non-invasive source for biomarker assessment a new study shows. According to the National Cancer Institute, the major cause of mortality in patients with cancer is caused by tumor cells that escape from the primary tumor into the bloodstream and travel through the circulation to distant sites where they develop into secondary tumors. These are called circulating tumor cells or CTC, and they provide a link...

2010-09-29 12:33:01

A novel technology can make nanoscale protein measurements, which scientists can use in clinical trials to learn how drugs work. "We are making progress toward the goal of understanding how drugs work in different individuals," said Alice C. Fan, M.D., instructor in the division of oncology at Stanford University School of Medicine. "Using new technologies makes it possible to measure effects of therapeutic agents in tumor cells and different cell populations within our patients. Now that we...

2010-09-28 20:53:42

A new disposable device based on advances in microfluidics may help identify advanced breast cancer patients who are candidates for therapy with the drug trastuzumab (Herceptin). The device is described in the American Institute of Physics' journal Biomicrofluidics. Aggressive breast cancers with poor prognosis typically have abnormal levels of the protein HER2 (the tyrosine kinase human epidermal growth factor receptor 2). The new elastomeric, rubber-like device is designed to efficiently...

2010-09-28 20:19:52

Circulating tumor cells (CTCs) may be a promising alternative, noninvasive source of tumor materials for biomarker assessment, according to data presented at the Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development. "The basic idea is that CTCs can provide real-time information about a patient's current disease state, acting as a 'liquid biopsy,'" said Siminder Kaur Atwal, Ph.D., senior research associate at Genentech. "They are much less invasive...

2010-06-07 08:00:00

Results Presented at ASCO 2010 Annual Meeting Confirm Acceptable Safety Profile and Evidence of Biological Activity Including Declines in Circulating Tumor Cells and Reductions in Tumor Markers BOTHELL, WA, and VANCOUVER, June 7 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) today announced final results from a Phase 1 trial. The primary purpose of this trial was to evaluate the safety and tolerability of OGX-427 up to doses of 1000 mg for the treatment of various...

2010-05-28 18:08:32

Researchers uncover that some circulating tumor cells may be worse than others Fox Chase Cancer Center investigators find that pancreatic cancer patients who have circulating tumor cells tend to have worse outcomes than patients without circulating tumor cells. Additionally, the team has uncovered evidence that not all circulating tumor cells are the same, and some may predict worse outcomes than others. Benjamin P. Negin, M.D., a medical oncology fellow at Fox Chase, will present the study...

2010-05-20 10:15:00

SAN DIEGO, May 20 /PRNewswire/ -- Biocept, Inc. ("Biocept"), an emerging leader in rare cell capture, announced today that the U.S. Patent and Trademark Office has issued a patent for Biocept's cell separation technology using a microfluidic device. U.S. patent #7,695,956 entitled "Device for Cell Separation and Analysis and Method of Using" protects Biocept's microflow device to isolate cells from a bodily fluid using a flow path where straight-line flow is interrupted by transverse posts...

2010-05-07 08:54:49

A new study of metastatic breast cancer shows that the number of circulating tumor cells patients have in their blood directly correlates with the length of their survival. Reported at the IMPAKT Breast Cancer Conference in Brussels, Belgium, the results have the potential to improve the delivery of personalized therapy to these patients. Circulating tumor cells --cancer cells found in a patient's bloodstream-- are detected in 50% to 80% of patients with metastatic breast cancer. Since 2004,...

2010-03-31 16:40:44

Technical improvements to a microchip-based device for detecting and analyzing tumor cells in the bloodstream are revealing cellular differences that may reflect a tumor's aggressiveness and long-term response to treatment. A report from the Massachusetts General Hospital (MGH) Center for Engineering in Medicine in the March 31 Science Translational Medicine describes refinements to the MGH-developed CTC-chip, which measures levels of circulating tumor cells (CTCs) in the blood stream, that...

9b9102b6a70bb60d91fd72361654c3ab1
2010-03-13 08:05:00

University of Maryland research may provide potential target for new therapies to limit metastasis of primary cancers Researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center have discovered that "microtentacles," or extensions of the plasma membrane of breast cancer cells, appear to play a key role in how cancers spread to distant locations in the body. Targeting these microtentacles might prove to be a new way to prevent or slow the growth of these secondary...