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Latest Clathrin Stories

2014-02-18 14:09:05

Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century. The study, published today in the journal eLife, is the first to outline the role of actin, a protein, in shutting down clathrin-dependent endocytosis during mitosis. Endocytosis is the process by which cells absorb molecules that are too large to pass through the plasma membrane, such as...

2013-12-31 23:24:37

Milk thistle extract has been used since ancient times for liver health and is currently used by many individuals with chronic hepatitis C infections, with only a limited understanding of its mode of action. Wyckoff, NJ (PRWEB) December 31, 2013 Previous research studies indicate that milk thistle and its main component silibinin inhibit HCV infection. A team of scientists led by J. Blaising* have conducted a study aimed at elucidating the mechanism of anti-HCV action of...

2013-08-08 15:15:20

Researchers at Warwick Medical School have identified the key role played by a team of proteins in the process of mitosis. Working out how to control them may give scientists a way to destroy cancerous cells. The study, published in The Journal of Cell Biology, highlights the role of a newly identified team of proteins, TACC3-ch-TOG-clathrin, in forming inter-microtubule bridges that stabilize the kinetochore fibers (K-fibers) used in mitosis. When a cell divides, it produces a mitotic...

2012-04-02 09:27:32

IFITM3 protein is critical to the structure and function of cellular machinery involved in blocking virus production Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system. This finding, published in the March 30, 2012, issue of Innate Immunity, sheds light on the cellular...

2011-10-07 13:50:00

Ascent Scientific, together with Freie Universität Berlin, The University of Newcastle and Children's Medical Research Institute today announced that they have entered into an exclusive licence, supply and distribution agreement for the clathrin inhibitors Pitstop 1TM and Pitstop 2TM for research. These novel compounds are the first rationally designed inhibitors of clathrin, and represent important tools for investigating essential cellular processes such as endocytosis. The agreement...

2009-06-25 11:45:26

In the bustling economy of the cell, little bubbles called vesicles serve as container ships, ferrying cargo to and from the port - the cell membrane. Some of these vesicles, called post-Golgi vesicles, export cargo made by the cell's protein factory. Scientists have long believed that other, similar vesicles handle the reverse function, importing life-supporting nutrients and proteins through an independent process. By using a finely honed type of microscopy to more precisely examine these...

2005-06-22 12:35:00

When it comes to gaining entry into cells, size matters. A team from Brown University and the Max Planck Institute for Metals Research has created a model that explains how viruses and other bioparticles slip inside cells without a special protein coating called clathrin. The secret, it seems, is to be average. Mid-sized nanomaterials "“ about 27 to 30 nanometers in diameter, or about 1,000 times thinner than a human hair "“ are optimal for cellular entry. In a research article to...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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