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Latest Complement factor I Stories

2014-03-31 16:27:38

OAKLAND, Calif., March 31, 2014 /PRNewswire/ -- Machaon Diagnostics today announced the availability of its "aHUS Genetic Panel(TM)" (patent pending) to genetically confirm atypical Hemolytic Uremic Syndrome (aHUS) with a turnaround time of 48 hours. The 48 hour timeframe is a dramatic advancement over other approaches which offer results in 4-13 weeks. The speed of the aHUS Genetic Panel(TM) allows the test to impact patient care in acute settings, enabling doctors to better serve...

2014-03-10 08:29:22

- Phase 2 Clinical Trial in aHUS and Other TMAs Expected to Begin Next Quarter - SEATTLE, March 10, 2014 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced positive data using OMS721, the lead human monoclonal antibody in Omeros' mannan-binding lectin-associated serine protease-2 (MASP-2) program, in ex vivo studies of endothelial activation relevant to the pathophysiology of human atypical hemolytic uremic syndrome (aHUS), a form of thrombotic microangiopathy (TMA)....

2014-01-16 08:27:51

New testing approach uses Next Gen Sequencing platform MILWAUKEE, Jan. 16, 2014 /PRNewswire/ -- BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of a comprehensive genetic evaluation using next generation sequencing (NGS) technology for patients with Atypical Hemolytic Uremic Syndrome (aHUS). BloodCenter is among the first to offer clinical diagnostics using NGS, providing a dramatically shortened timeline for obtaining test results for this...

2011-02-04 12:33:00

This week, the highly-respected US Academy of Sciences journal (PNAS) published an article describing how the first line of defence of the human immune system distinguishes between microbes and the body's own structures. The basis of this recognition mechanism has been unclear since the key protein components were discovered over 30 years ago "“ and has now finally been cracked by a collaboration between high-level research groups at the University of Helsinki, Finland. When a microbe...

2010-12-27 13:49:27

A team from the University of Pennsylvania School of Medicine and Utrecht University has deciphered a key step in an evolutionarily old branch of the immune response. This system, called complement, comprises a network of proteins that "complement" the work of antibodies in destroying foreign invaders. It serves as a rapid defense mechanism in most species from primitive sponges to humans. In a study published in the December 24 issue of Science, the groups of John Lambris, PhD, the Dr. Ralph...

2010-12-06 14:15:26

Sugar molecules coat every cell in our bodies and play critical roles in development and disease, yet the components of these "glycans" have been difficult for scientists to study, because of their complexity. Researchers at Emory University School of Medicine have adapted gene chip microarray technology to the study of glycans, with an approach they call "shotgun glycomics." The Emory team has developed a new chemical method for attaching a fluorescent dye to glycans purified from cells. The...

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2009-06-17 14:40:00

How molecules of the oldest branch of the human immune system have interconnected has remained a mystery. Now, two new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding problems of the body attacking itself.The structures may pave the way to more efficient therapeutics for such complement-mediated diseases as age-related macular degeneration, rheumatoid...

2008-12-22 11:30:10

Study holds hope for next generation hemophilia treatment Researchers have made several, subtle changes in the structure of a key protein, dramatically increasing its ability to drive blood clotting, according to a study published in a December edition of the Journal of Thrombosis and Haemostasis. The findings have profound implications for the treatment of hemophilia, the inherited blood disorder that causes easy or excessive bleeding in 30,000 Americans. In most cases, hemophilia is caused...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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