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Latest Corynebacterineae Stories

2011-10-04 09:27:14

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body´s defense. New research suggests this represents a novel mechanism in the microbe´s evolving efforts to remain hidden from the human immune system. Researchers found that the TB bacterium has a molecule on its outer surface called lipomannan that can stop production of an important protein in the body´s immune cells that helps contain TB infection and...

2011-09-08 10:14:31

(Ivanhoe Newswire) — A potential vaccine against tuberculosis (TB) has been found to completely eliminate TB bacteria from infected tissues in some mice. The vaccine was made from a strain of bacteria that are unable to avoid its host´s first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that remembers the bacteria and protects against future infection. Tuberculosis, an infectious disease caused by...

2011-09-06 12:45:41

  An experimental vaccine composed of a genetically modified bacterium closely related to the bacterium that causes tuberculosis (TB) has been found to protect mice against TB infection, according to a study appearing online September 4 in the journal Nature Medicine. The research was funded in part by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health. TB, a respiratory disease that according to World Health Organization estimates...

2011-09-05 11:16:45

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that can protect against future infections. The research, by scientists at the Howard Hughes Medical Institute,...

TB Vaccine Shows Promising Results In Lab Tests
2011-09-05 04:48:52

  Scientists at the Albert Einstein College of Medicine reported on Sunday that a vaccine they developed for tuberculosis had shown promising results during early laboratory testing in mice. Professor William Jacobs and colleagues, who published their findings in the journal Nature Medicine on Sunday, worked with Mycobacterium smegmatis, a species similar to tuberculosis that is lethal in mice but harmless to humans. "The researchers created a version of M. smegmatis lacking a...

2011-08-17 12:19:16

Published in Journal of Applied Microbiology Researchers have discovered a faster, cheaper method for the diagnosis of tuberculosis (TB). A major barrier in TB prevention, especially in developing countries, is that diagnosis is slow and costly. Dr Olivier Braissant and his colleagues have developed a method which could potentially decrease the time taken to make a diagnosis. Their method is also cheaper than the current fastest methods. This research has been published today in the Society...

2011-08-01 16:03:14

New research published in the Journal of Leukocyte Biology suggests that lack of expression of innate immune system receptor may play a critical role in the immune response to mycobacterial infections Are you genetically predisposed to tuberculosis? Scientists may now be able to answer this question and doctors may be able to adjust their therapeutic approach based on what they learn. That's because new research presented in the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests...

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2011-07-14 08:40:40

Localized badger culling in response to bovine tuberculosis (TB) outbreaks increases the risk of infection in nearby herds, according to a new analysis. The study, by researchers at the Medical Research Council (MRC) Centre for Outbreak Analysis and Modelling at Imperial College London, was published July 13 in the Royal Society journal Biology Letters. The findings come as the Government prepares to decide whether to license farmers to organize the widespread culling of badgers over areas of...

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2011-04-28 10:40:00

Leprosy cases reported in the US only number around 150 per year and the majority of these cases can be attributed to travel to places such as Angola, Brazil and India. However, Scientists have identified a source for some of the unexplained cases that appear in the southern US - the nine-banded armadillo. DNA samples were taken from 33 wild armadillos in Arkansas, Alabama, Louisiana, Mississippi and Texas. Armadillos are one of the very few mammals that can carry the bacteria causing the...

2011-04-28 07:27:19

(Ivanhoe Newswire) -- A new study published in the New England Journal of Medicine reveals a new strain of leprosy has surfaced in the Southern United States. Leprosy is a chronic, mildly contagious disease of tropical and subtropical regions with a long and extensive history. Until the 20th century, infected people were ostracized from society or at best segregated and cared for in isolated leper colonies. Today, the disease is entirely curable through multidrug therapy, though tissue damage...


Latest Corynebacterineae Reference Libraries

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2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

0_b33ceb9bb58e871b533817f5a6385ba1
2011-04-25 15:56:48

Mycobacterium smegmatis is 3.0 to 5.0 µm long with a bacillus shape, an acid-fast bacterial species in the phylum Actinobacteria. It can be stained by Ziehl-Neelsen method and the auramine-rhodamine fluorescent method. It was first reported in 1884. Alvarez and Tavel found organisms similar to Lustgarten, who first discovered Mycobacterium. This organism was later named M. smegmatis. It is considered a non-pathogenic microorganism although, in rare cases, it can cause disease. M....

0_da8e53266fdcbd2830a775ec887963be
2011-04-25 15:36:41

Mycobacterium leprae, mostly found in warm tropical countries, is a bacterium that causes leprosy (Hansen's disease). It is an intracellular, pleomorphic, acid-fast bacterium. M. leprae is an aerobic rod-shaped surrounded by the characteristic waxy coating unique to mycobacteria tuberculosis. Due to its thick waxy coating, M. leprae stains with a carbol fuscin rather than with the traditional Gram stain. Gerhard Armauer Hansen first discovered it in 1873. It was the first bacterium to be...

45_255d6ba67dfe6f32b9c7c31f338bf912
2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

0_a16d5f8c7a5fecb318cce3c15433fb95
2011-04-15 14:19:47

Corynebacterium diphtheriae is a pathogenic bacterium that causes diphtheria. It was discovered in 1884. There are four subspecies C. diphtheriae mitis, C. diphtheriae intermedius, C. diphtheriae gravis, and C. diphtheriae belfanti. They all are a little bit different in their colonial morphology and biochemical properties such as the ability to metabolize certain nutrients. The diphtheria toxin gene is encoded by a bacteriophage which is found in toxigenic strain. A gram stain is...

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Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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