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Latest Cowden syndrome Stories

2013-02-27 10:32:37

Lynch Syndrome is a heritable genetic mutation that causes colorectal, endometrial and other cancers. A cooperative study that included the University of Colorado Cancer Center, published in this month´s issue of the Journal of the National Cancer Institute, revises the risk of colorectal cancer down but other cancers up for women with Lynch Syndrome who have had endometrial cancer. “This new information helps patient care in two important ways. First, it helps us counsel women...

2013-02-25 13:38:04

Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumor-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumor process, make the cancer tumor more sensitive to chemotherapy and to prevent the development of resistance. The findings, which are published in the scientific journal Nature Structural and Molecular Biology, can be of significance in the future development of cancer drugs....

2012-03-08 06:12:15

(Ivanhoe Newswire) — We dream of a world where we can eat whatever we like and not worry about the consequences, like weight gain and health issues, and now we might be a step closer. A new study shows mice with an extra dose of a known anti-cancer gene lose weight even as their appetites grow and also live longer. In a case study, researchers studied a tumor suppressor commonly lost in human cancers. Mice were given an extra dose of a known anti-cancer gene, known as Pten. Not only...

2012-03-06 23:05:23

In a perfect world, we could eat to our heart's content without sacrificing our health and good looks, and now it appears that maybe we can. Mice with an extra dose of a known anti-cancer gene lose weight even as their appetites grow. Not only that, but according to the report in the March issue of the Cell Press journal Cell Metabolism, the animals also live longer, and that isn't just because they aren't getting cancer, either. One of the animals' youthful secrets is hyperactive brown...

2012-02-14 11:43:24

An international study led by the University of Melbourne has provided a clearer understanding of the cancer risks associated with the genetic mutation Lynch syndrome, a finding that could lead to earlier detection of a wide range of cancers in sufferers. People with Lynch syndrome have a genetic mutation that gives them a high risk of several types of cancer including bowel cancer.  The genes that are damaged can´t repair any errors that occur in our DNA. The study, which has...

2011-10-17 13:01:41

Gene promotes prostate cancer when 'turned on,' breast cancer when “turned off” Researchers at Cleveland Clinic have discovered that a gene — known as an androgen receptor (AR) — is found in both prostate and breast cancers yet has opposite effects on these diseases. In prostate cancer, the AR gene promotes cancer growth when the gene is "turned on." In breast cancer, the AR gene promotes cancer growth when the gene is "turned off," as is often the case after...

2011-06-06 08:00:10

(Ivanhoe Newswire) -- Mayo Clinic researchers have found a mutant gene, which was long thought to accelerate tumor growth in thyroid cancer patients, actually inhibits the spread of cancerous cells. Thyroid cancer is the sixth most common cancer in the world. Between 15 percent and 20 percent of all thyroid cancers are follicular, which is a type that is more aggressive. Distinguishing between benign and malignant follicular thyroid cancer is often challenging for doctors because an accurate...

2011-01-10 14:04:38

Large study offers more accurate diagnosis, guide to genetic testing Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers. The research has created a diagnostic scoring system that improves on established criteria. Led by Charis Eng, M.D., Ph.D., Chair of the Genomic Medicine Institute at the Lerner...

2010-03-30 13:52:42

COLUMBUS, Ohio "“ An important gene that normally protects the body against cancer can itself cause a variety of cancers depending on the specific mutation that damages it, according to a new study by investigators at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James). The study examined mutations in a gene called PTEN. People who inherit a mutated copy of this gene have Cowden syndrome, a...

2009-04-07 09:16:10

Scientists know a protein gene called PTEN is a major tumor-suppressor. When it's reduced or mutated, cancers can grow. Researchers from the University of Texas M.D. Anderson Cancer Center have discovered a second gene that appears to protect PTEN, a finding that could one day lead to new treatments for cancers of the breast and other organs. The new gene is called Rak, and it works to stabilize PTEN by attaching a phosphate group to the protein, thus blocking an enzyme that leads to its...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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