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Last updated on April 23, 2014 at 13:36 EDT

Latest Creutzfeldt–Jakob disease Stories

2013-03-13 17:59:04

Aggregation in CJD likely leads to iron imbalance and brain cell death An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found. The breakthrough follows discoveries that certain proteins found in the brains of Alzheimer's and Parkinson's patients also regulate iron. The results suggest that neurotoxicity by the form of iron, called...

2012-11-30 16:13:59

Prion diseases represent a family of neurodegenerative disorders associated with the loss of brain cells and caused by proteins called prions (derived from 'protein' and 'infection'). The diseases are found in both humans and animals, such as Creutzfeld-Jakob disease and mad cow disease respectively. Although mostly harmless, prions can transform into infectious agents, which accumulate in the brain and destroy the nervous tissue. But how exactly does the accumulation of prions cause...

Mad Cow Detection Hope
2012-09-13 08:30:04

April Flowers for redOrbit.com - Your Universe Online Medical researchers from the University of Melbourne believe that a simple blood test for Creutzfeldt-Jakob Disease and Bovine Spongiform Encephalopathy, aka Mad Cow disease, is a step closer following a recent breakthrough. Using newly available genetic sequencing, researchers have discovered cells infected with prions (the infectious protein responsible for these diseases) release particles which contain easily recognized signature...

2012-07-23 20:52:59

A team of University of Alberta researchers has identified a new class of compounds that inhibit the spread of prions, misfolded proteins in the brain that trigger lethal neurodegenerative diseases in humans and animals. U of A chemistry researcher Frederick West and his team have developed compounds that clear prions from infected cells derived from the brain. "When these designer molecules were put into infected cells in our lab experiments, the numbers of misfolded proteins...

Possible Way To Prevent Brain Cell Death Discovered
2012-05-07 03:29:28

In a new study, a team of UK researchers have reportedly found a way to prevent brain cell death in mice -- a discovery which could ultimately lead to improved treatments for Alzheimer's, Parkinson's, and other neurodegenerative ailments in humans. According to BBC News Health and Science Reporter James Gallagher, scientists at the University of Leicester studied prion disease, which affects mice in much the same way as Alzheimer's, Parkinson's, Huntington's and Creutzfeld-Jacob Disease...

2012-04-24 10:26:05

Consumers Can Be Assured that U.S. Beef Remains Safe WASHINGTON, April 24, 2012 /PRNewswire-USNewswire/ -- The following is a statement by AMI Executive Vice President James H. Hodges: "U.S. beef products are among the safest in the world and USDA's announcement today confirms that the U.S. animal disease surveillance system works to protect our herds and the public. USDA announced today that a dairy cow that died in California has tested positive for BSE. The animal was never...

2012-04-23 13:12:30

Prion proteins may be best known for their role in infectious diseases, but not all of them are destructive, new research shows One of the greatest mysterious in cellular biology has been given a new twist thanks to findings reported in Science. Researchers at the RIKEN Brain Science Institute show that prions, proteins that transmit heritable information without DNA or RNA, can contribute to drug resistance and cellular adaptation. Their discovery of a yeast prion with these properties...

2012-04-11 14:44:45

Computer modeling supports theory that many dementias spread like prion diseases A new technique for analyzing brain images offers the possibility of using magnetic resonance imaging (MRI) to predict the rate of progression and physical path of many degenerative brain diseases, report scientists at the San Francisco VA Medical Center and the University of California, San Francisco. The technique, developed by SFVAMC scientists in collaboration with a team led by Bruce Miller, MD,...

2012-03-21 21:24:47

Weill Cornell scientists say the program might help patients manage their disease Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of...

2012-03-05 10:53:40

A University of Alberta research team has discovered that technology commonly used to decontaminate food industry equipment can also rid meat processing plants of lethal microbial material responsible for the human version of the ailment Mad Cow disease. U of A microbiology professors Mike Belosevic and Norm Neumann and engineering professor Mohamed Gamal El-Din demonstrated that infectious proteins found in the brain matter of cattle can be eradicated from water treated with ozone. The...