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Latest Creutzfeldt–Jakob disease Stories

2012-03-21 21:24:47

Weill Cornell scientists say the program might help patients manage their disease Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of...

2012-03-05 10:53:40

A University of Alberta research team has discovered that technology commonly used to decontaminate food industry equipment can also rid meat processing plants of lethal microbial material responsible for the human version of the ailment Mad Cow disease. U of A microbiology professors Mike Belosevic and Norm Neumann and engineering professor Mohamed Gamal El-Din demonstrated that infectious proteins found in the brain matter of cattle can be eradicated from water treated with ozone. The...

2012-02-10 00:09:01

Findings Suggest New View of “Mad Cow” and Other Neurodegenerative Diseases Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in “mad cow” disease, but is at least 10 times more lethal than larger prion species. This toxic single molecule or “monomer” challenges the prevailing concept that neuronal damage is linked to the toxicity of prion protein...

2011-12-01 11:11:07

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature. Findings published this month in the peer-reviewed journal, Public Library of Science (PLoS) Pathogens, demonstrate that up to seven months before an animal shows physical signs of having a prion infection, a particular prion protein in the brain was being eradicated. This member of the prion family is known...

2011-10-04 10:47:20

The brain damage that characterizes Alzheimer's disease may originate in a form similar to that of infectious prion diseases such as bovine spongiform encephalopathy (mad cow) and Creutzfeldt-Jakob, according to newly published research by The University of Texas Health Science Center at Houston (UTHealth). "Our findings open the possibility that some of the sporadic Alzheimer's cases may arise from an infectious process, which occurs with other neurological diseases such as mad cow and...

2011-09-14 22:24:56

Finding opens possibility of treating brain-wasting mad cow disease In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases. The researchers, led by Thomas Wisniewski, MD, professor of neurology, pathology and psychiatry, report their findings in today's online...

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2011-08-21 14:47:01

Children who received pituitary growth hormone treatments after 1977, when scientists started purifying them, are less likely to develop Creutzfeldt - Jakob disease (CJD) than those who received earlier, unpurified treatments, a team of researchers has discovered. The authors of the study, which was published in The Journal of Clinical Endocrinology & Metabolism (JCEM) earlier this month, were looking to provide updated CJD information to prior U.S. National Hormone and Pituitary...

2011-08-09 08:03:20

A person's ability to battle viruses at the cellular level remarkably resembles the way deadly infectious agents called prions misfold and cluster native proteins to cause disease, UT Southwestern Medical Center researchers report. This study marks the first discovery of so-called "good" prion-like proteins in human cells and the first to find such proteins involved in innate immunity: the way the body recognizes and responds to threats from viruses or other external agents, said Dr. Zhijian...

2011-07-25 13:29:02

It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals. Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of "seed" to get started. Biochemists at Emory University School of Medicine have identified a yeast protein called Lsb2...

2011-05-26 20:49:39

Unlocking the mechanisms that cause neurodegenerative prion diseases may require a genetic key, suggest new findings reported by University of Illinois at Chicago distinguished professor of biological sciences Susan Liebman. Prions can turn a normal protein into a misfolded form. One prion in mammals promotes progressive neurodegenerative disorders like "mad cow" disease that often prove fatal. But how this process happens remains an open question for scientists. Prions have been found to...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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