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Last updated on April 16, 2014 at 12:22 EDT

Latest Creutzfeldt–Jakob disease Stories

2010-12-17 16:15:21

Findings Point to Normal Prion Protein as Most Effective Therapeutic Target for "Mad Cow" and Related Diseases Scientists from the Florida campus of The Scripps Research Institute have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad cow disease," have the ability to adapt to survive in a new host environment. In this regard, although they lack DNA and RNA, they behave much like viruses,...

2010-12-03 13:27:50

A fast test to diagnose fatal brain conditions such as mad cow disease in cattle and Creutzfeldt-Jakob disease in humans could be on the horizon, according to a new study from National Institutes of Health scientists. Researchers at NIH's National Institute of Allergy and Infectious Diseases (NIAID) have developed a highly sensitive and rapid new method to detect and measure infectious agents called prions that cause these diseases. "Although relatively rare in humans and other animals, prion...

2010-12-01 21:11:38

New research in the FASEB Journal suggests that plasminogen, which helps break down blood clots, puts rogue prion proteins into overdrive, causing devastating brain diseases The joy of a juicy hamburger could make a comeback thanks a new discovery by scientists from the University of Kentucky. In a new research report in the December 2010 print issue of The FASEB Journal (http://www.fasebj.org), scientists found that a protein our body uses to break up blood clots speeds up the progress of...

2010-10-19 20:39:16

The eyes of sheep infected with scrapie "“ a neurological disorder similar to mad cow disease "“ return an intense, almost-white glow when they're hit with blue excitation light, according to a research project led by Iowa State University's Jacob Petrich. The findings suggest technologies and techniques can be developed to quickly and noninvasively test for transmissible spongiform encephalopathies, progressive and fatal neurological diseases such as mad cow disease in cattle and...

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2010-09-12 09:50:00

A cow's eyes may show signs of neurological disorders such as mad cow disease, according to scientists.Noticing the signs early enough may help prevent infected meat from reaching the food supply.Researchers at the Iowa State University examined the retinas of sheep infected with scrapie -- a disease similar to mad cow disease. The researchers stated in the journal Analytical Chemistry that the sick sheep's eyes had a unique "glow."People who eat contaminated meat may contract a brain-wasting...

2010-08-13 16:25:04

Variably protease-sensitive prionopathy shares genotype characteristics with Creutzfeldt-Jakob disease A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since Creutzfeldt-Jakob disease (CJD) was reported in the 1920s. The landmark finding from the National Prion Disease Pathology Surveillance Center at Case Western Reserve University is published in...

2010-07-27 13:46:13

Metal surfaces spur conversion of normal prion protein into disease-causing prions In a startling new study that involved research on both sides of the Atlantic, scientists from The Scripps Research Institute in Florida and the University College London (UCL) Institute of Neurology in England have shown for the first time that abnormal prions, bits of infectious protein devoid of DNA or RNA that can cause fatal neurodegenerative disease, can suddenly erupt from healthy brain tissue. The...

2010-07-08 14:00:14

"Based on the monitoring records of spongiform encephalopathy in two Nordic countries, we studied the possibility of transmission of the sporadic form of CJD through general surgery", explains Jesús de Pedro, main author of the study and head of prion monitoring in patients at the National Epidemiology Centre of the Carlos III Health Institute. The finding, published recently in the Journal of Neurology, Neurosurgery & Psychiatry, reveals that, with a few exceptions,...

2010-06-15 00:52:29

Prion diseases are lethal neurodegenerative disorders that include Creutzfeldt-Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE; commonly known as mad cow disease) in cows. A team of researchers, led by Adriano Aguzzi and Christina Sigurdson, at UniversitätsSpital Zrich, Switzerland, has generated data in mice that provides greater understanding of the factors that determine how easy it is for prion diseases to be transmitted to a new host species. This information...

2010-04-27 06:48:00

PARIS, April 27, 2010 /PRNewswire/ -- - French Health Products Safety Agency AFSSAPS Approves STERRAD(R) Hydrogen Peroxide Gas Plasma Technology for Total Inactivation of Protein-based Infectious Agents Linked to Fatal Brain Diseases Advanced Sterilization Products (ASP) announced today that the French Health Products Safety Agency, AFSSAPS, will approve the low-temperature hydrogen peroxide gas plasma STERRAD(R) NX(TM) and the STERRAD(R) 100NX(TM) Sterilization Systems for...