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Latest Creutzfeldt–Jakob disease Stories

2009-09-28 15:31:24

A University of Toronto-led team has uncovered the evolutionary ancestry of the prion gene, which may reveal new understandings of how the prion protein causes diseases such as bovine spongiform encephalopathy (BSE), also known as "mad cow disease." Diseased prion proteins are responsible for the fatal neurodegenerative Creutzfeldt-Jakob disease (CJD) in humans, and BSE, scrapie and chronic wasting disease (CWD) in livestock. Overall, this work holds promise for efforts to reveal the...

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2009-09-10 07:38:02

According to a study published on Wednesday, it appears that a variety of prion disease found in deer may be spread through the fecal matter of infected animals even when they exhibit no symptoms of the illness.  Researchers say that their finds on the deadly brain disorder known as chronic wasting disease (CWD)"”a close cousin of the infamous mad-cow disease"”may have significant ramifications for farmers. The research was led by Nobel laureate Stanley Prusiner at the...

2009-08-21 12:37:32

A new study shows that nervous system integrity and axonal properties may play a key role in prion diseases. The findings, from researchers at the Rudolf Virchow Center and the Institute of Virology of the University of Wrzburg, expand our understanding of the development of prion disease and suggest novel targets for therapeutic and diagnostic approaches in its early stages. Details are published August 21 in the open-access journal PLoS Pathogens.Despite growing awareness of prion diseases,...

2009-08-19 11:06:03

A British expert on the human form of mad cow disease says it is essential that coroners test the brains and spleens of all young people who die. Professor John Collinge says without post-mortem tests for the infection it is impossible to get accurate information on how many people in Britain may be carrying it, The Times of London reported Wednesday. Collinge, a member of a government panel monitoring the progress of spongiform encephalopathy, or mad cow disease, says systematic testing is...

2009-07-30 11:54:05

Data from an ongoing multi-year study suggest that people who consume deer and elk with chronic wasting disease (CWD) may be protected from infection by an inability of the CWD infectious agent to spread to people. The results to date show that 14 cynomolgus macaques exposed orally or intracerebrally to CWD remain healthy and symptom free after more than six years of observation, though the direct relevance to people is not definitive and remains under study. Cynomolgus macaques often are...

2009-07-25 14:54:13

University of Wisconsin Hospital staff appropriately handled a patient who died of Creutzfeldt-Jakob, a deadly brain disease, hospital officials said. The hospital this week notified 53 patients they have an extremely low risk of contracting the disease, despite being operated on with potentially contaminated surgical instruments used on the patient with the disease, The Wisconsin State Journal reported Saturday. The woman, in her 50s, died Tuesday at the hospital of what doctors called...

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2009-06-27 11:15:00

Scientists have raised concern over the potential for people to contract Creutzfeldt Jakob disease "” the human form of "mad cow disease" "” from eating farmed-raised fish that are fed byproducts rendered from cows, Reuters reported. Bovine spongiform encephalopathy, which is commonly referred to as Mad cow disease, is a fatal brain disease in cattle that may cause Creutzfeldt Jakob disease in humans who eat infected cow parts, scientists said. Neurologist Dr. Robert P. Friedland...

2009-06-11 11:00:00

U.S. medical scientists say they have determined how prion proteins responsible for mad cow disease and related illnesses destroy healthy brain tissue. The National Institutes of Health researchers said their findings will help in developing potential treatments for prion diseases or, perhaps, ways to prevent them. The research, conducted at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, determined the proteins responsible for the disorders, known as...

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2009-06-08 11:15:00

New research has shown that a rogue protein thought to cause Alzheimer's can spread through the brain, turning healthy tissue bad, BBC News reported.The tau protein may share characteristics with the prion proteins that cause vCJD. Scientists found it triggered formation of protein tangles linked to Alzheimer's after they injected it into the brains of healthy mice.But the study, published in the Nature Cell Biology, said this did not mean tau could be passed from person to person.Tau is a...

2009-05-29 08:15:00

Development may help shed light on disease in animals and protect human populationsCurrent tests to identify specific strains of infectious prions, which cause a range of transmissible diseases (such as mad cow) in animals and humans, can take anywhere from six months to a year to yield results "“ a time-lag that may put human populations at risk.Now, a group of scientists from The Scripps Research Institute's Florida campus have developed a new method that cuts this critical time lag...