Quantcast

Latest CRISPR Stories

2014-03-04 23:24:07

The revolutionary NickaseNinja™ combines a tandem pair of gRNAs in a single vector. Menlo Park, CA (PRWEB) March 04, 2014 DNA2.0 today announced the release of a set of CRISPR/Cas9 tools for genome editing and engineering. At the heart of DNA2.0’s CRISPR toolset is the revolutionary NickaseNinja system, which offers the high fidelity editing of Cas9 nickase plus guide RNA (gRNA) pairs, in a convenient single-vector format. By co-expressing two guide RNAs using dual RNA polymerase...

2014-02-25 00:21:09

Medal recognizes work studying RNA BETHESDA, Md., Feb. 25, 2014 /PRNewswire/ -- The Foundation for the National Institutes of Health (FNIH) has selected Jennifer Doudna, Ph.D., a Professor from the University of California, Berkeley, as the second winner of its Lurie Prize in the Biomedical Sciences. Doudna, a Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology, will be presented the Lurie Prize medal and a $100,000 honorarium on May 20 in...

2014-02-07 12:52:46

Berkeley Researchers Show Expanded Role for Guide RNA in Cas9 Interactions with DNA The potential is there for bacteria and other microbes to be genetically engineered to perform a cornucopia of valuable goods and services, from the production of safer, more effective medicines and clean, green, sustainable fuels, to the clean-up and restoration of our air, water and land. Cells from eukaryotic organisms can also be modified for research or to fight disease. To achieve these and other...

Precise Gene Modification In Monkeys Paves Way For Valuable Human Disease Models
2014-01-30 15:58:45

Cell Press Monkeys are important for modeling diseases because of their close similarities to humans, but past efforts to precisely modify genes in primates have failed. In a study published by Cell Press January 30th in the journal Cell, researchers achieved precise gene modification in monkeys for the first time using an efficient and reliable approach known as the CRISPR/Cas9 system. The study opens promising new avenues for the development of more effective treatments for a range of...

2014-01-27 13:30:39

A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. In a report receiving advance online publication in Nature Biotechnology, Massachusetts General Hospital (MGH) investigators describe how adjusting the length of the the guide RNA (gRNA) component of the synthetic enzymes called CRISPR-Cas RNA-guided nucleases (RGNs) can substantially reduce the occurrence of DNA mutations at sites other than the intended target, a limitation the team had previously...

2013-12-24 13:35:52

Genetic screening identifies genes driving resistance with a guide RNA library Researchers have developed a method to create a comprehensive library of mutations across all genes in the mouse genome. This library can be used to examine the role of every gene in different cell types. CRISPR technology uses the DNA-cutting enzyme Cas9, with the help of a guide RNA sequence, to find and modify genetic targets. Scientists can easily engineer multiple new guide RNAs using standard molecular...

Technique Accelerates Gene Discovery
2013-12-13 08:05:12

redOrbit Staff & Wire Reports - Your Universe Online Researchers working to decipher the role of genes since the completion of the Human Genome Project may see their efforts accelerated by a new approach that lets them permanently and selectively delete genes from a cell's DNA. The new system, known as CRISPR, was developed by researchers at MIT, the Broad Institute, and the Whitehead Institute, and should allow scientists to study the entire genome at once. In two new papers...

2013-06-24 15:07:59

Results indicate need to improve precision of CRISPR-Cas RNA-guided nucleases In the past year a group of synthetic proteins called CRISPR-Cas RNA-guided nucleases (RGNs) have generated great excitement in the scientific community as gene-editing tools. Exploiting a method that some bacteria use to combat viruses and other pathogens, CRISPR-Cas RGNs can cut through DNA strands at specific sites, allowing the insertion of new genetic material. However, a team of Massachusetts General...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
Related