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Latest CRISPR Stories

2013-06-24 15:07:59

Results indicate need to improve precision of CRISPR-Cas RNA-guided nucleases In the past year a group of synthetic proteins called CRISPR-Cas RNA-guided nucleases (RGNs) have generated great excitement in the scientific community as gene-editing tools. Exploiting a method that some bacteria use to combat viruses and other pathogens, CRISPR-Cas RGNs can cut through DNA strands at specific sites, allowing the insertion of new genetic material. However, a team of Massachusetts General...

2013-04-30 23:35:26

HZI researchers discover multiple versions of microbial defense genes that lend themselves to being exploited by biotechnology Even bacteria have a kind of “immune system” they use to defend themselves against unwanted intruders — in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions....

2013-04-15 12:01:51

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system. The results are scheduled for publication Sunday, April 14 in Nature. CRISPR is itself a sort of immune system for bacteria. Its function was discovered by dairy industry researchers seeking to prevent phages, the viruses that infect bacteria, from ruining the cultures used to make cheese and yogurt. Bacteria...

2012-06-29 10:42:42

Genetic engineers and genomics researchers should welcome the news from the Lawrence Berkeley National Laboratory (Berkeley Lab) where an international team of scientists has discovered a new and possibly more effective means of editing genomes. This discovery holds potentially big implications for advanced biofuels and therapeutic drugs, as genetically modified microorganisms, such as bacteria and fungi, are expected to play a key role in the green chemistry production of these and other...

Human Microbiome Project Exposes Battle History Between Bacteria, Viruses In Human Body
2012-06-13 19:55:49

Informatics, biology team demonstrates role of foreign DNA strands in life-supporting bacteria An Indiana University team of researchers has conducted the most in-depth and diverse genetic analysis of the defense systems that trillions of micro-organisms in the human body use to fend off viruses. The work is among a collection of 16 research papers released today by the Human Microbiome Project Consortium, a National Institutes of Health-led effort to map the normal microbial make-up of...

2012-01-05 16:40:50

Discovery reveals new possibility for gene silencing in bacteria and other organisms The knowledge that bacteria possess adaptable immune systems that protect them from individual viruses and other foreign invaders is relatively new to science, and researchers across the globe are working to learn how these systems function and to apply that knowledge in industry and medicine. Now, a team of University of Georgia researchers has discovered how to harness this bacterial immune system to...

2011-09-22 19:17:28

Berkeley Lab Researchers Resolve Sub-nanometer Structure of Cascade, an Ally for Human Immune System A complex of proteins in the bacterium E.coli that plays a critical role in defending the microbe from viruses and other invaders has been discovered to have the shape of a seahorse by researchers with the U.S Department of Energy´s Lawrence Berkeley National Laboratory (Berkeley Lab). This discovery holds far more implications for your own health than you might think. In its...

2011-05-18 00:03:15

Researchers at the University of Alberta have taken an important step in understanding an immune system of bacteria, a finding that could have implications for medical care and both the pharmaceutical and dairy industries. In research published in the high impact journal Nature Structural & Molecular Biology, Andrew MacMillan and co-workers in his lab have described the first step of the immune response of bacterial cells. Scientists had previously found that a bacterial virus, called a...

2010-12-13 13:39:00

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease. Viruses can attack and change the composition of bacterial communities, yet little is known about how this might influence human health. In a study published online today in Genome Research (www.genome.org), scientists have performed the first metagenomic analysis of a bacterial immune system in humans over time, finding that the defenses of the oral...

2010-11-04 17:57:08

A team of Universit© Laval and Danisco researchers has just unlocked the secret of bacteria's immune system. The details of the discovery, which may eventually make it possible to prevent certain bacteria from developing resistance to antibiotics, are presented in today's issue of the scientific journal Nature. The team led by Professor Sylvain Moineau of Universit© Laval's Department of Biochemistry, Microbiology, and Bioinformatics showed that this mechanism, called CRISPR/Cas,...