Latest Crohn's disease Stories
LONDON and MOUNTAIN VIEW, Calif., Jan. 12, 2011 /PRNewswire/ -- GlaxoSmithKline (GSK) and ChemoCentryx, Inc. announced today that the first patient with Crohn's disease has initiated treatment in the initial pivotal induction study comparing Traficet-EN, now designated GSK1605786 ('786), to placebo. This marks the start of the Phase III clinical development programme for '786 for the treatment of this serious and chronic disease. '786 is a non-biologic, orally bioavailable CCR9 antagonist....
NEW YORK, Jan. 11, 2011 /PRNewswire/ -- In 2010, over 2,000 people ran, walked, or cycled with the Crohn's & Colitis Foundation's endurance training and fundraising program, Team Challenge. These participants at all fitness levels raised $8 million for research, education, and support services for patients suffering from Crohn's disease and ulcerative colitis, chronic and often debilitating digestive diseases affecting over 1.4 million Americans. To view the multimedia assets...
OKLAHOMA CITY, Jan. 6, 2011 /PRNewswire/ -- Altheus Therapeutics, Inc., announced that it has completed a two dose, double-blind, active-controlled Phase I clinical trial of the safety and tolerability of Zoenasa(TM) Rectal Suspension in adult patients with left-sided, or distal, ulcerative colitis. No serious adverse events were experienced by patients in this study. "We are excited to have achieved this milestone, as it prepares Altheus to begin our planned Phase II clinical program to...
WAYLAND, Mass., Jan. 5, 2011 /PRNewswire/ -- Avaxia Biologics, Inc., a privately-held biotech company developing an innovative platform technology to deliver orally-active antibodies to the gastrointestinal tract, announced today that it has generated compelling pre-clinical data in animal models of inflammatory bowel disease (IBD). Avaxia's orally administered anti-TNF product AVX-470 significantly reduced disease severity in three different animal models and showed superior efficacy to an...
Each year, the holidays present a bit of a conundrum. Everybody likes to look their best for parties and gatherings, yet at the same time, they are surrounded by more food and drink than any other time of year. Beltsville, MD (Vocus) December 20, 2010 Each year, the holidays present a bit of a conundrum. Everybody likes to look their best for parties and gatherings, yet at the same time, they are surrounded by more food and drink than any other time of year. Christmas especially is a...
Scientists at the University of California, San Diego School of Medicine have described for the first time a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, providing novel insights into human inflammatory bowel disease (IBD) and potential new treatments.The research, led by Jose M. Gonzalez-Navajas, PhD, and Eyal Raz, MD, a professor of medicine at UC San Diego, is published as a Brief Definitive Report in the December issue of The Journal of...
The Crohn's & Colitis Foundation was proud to honor three leaders in the field of IBD research and treatment on Friday, December 10th at its 2010 Advances in Inflammatory Bowel Diseases Clinical & Research Conference (http://www.AdvancesInIBD.com) in Hollywood, Florida. New York, NY (Vocus) December 13, 2010 The Crohn's & Colitis Foundation was proud to honor three leaders in the field of IBD research and treatment on Friday, December 10th at its 2010 Advances in Inflammatory...
An international team of researchers led by the University of East Anglia (UEA) have developed a new kind of endoscope to aid the early detection and diagnosis of inflammatory bowel disease.The Confocal Laser Endomicroscope (CLE) contains a powerful microscope which allows clinicians to view the bacteria that are thought to trigger diseases of the bowel such as Crohn's disease and ulcerative colitis."Bacteria within the wall of the gut are already believed to play an important role in...
Researchers at the University of Queensland Diamantina Institute in Brisbane, Australia, have found that a form of spinal arthritis is genetically linked to Inflammatory Bowel Disease. The study will be published on December 2 in the open-access journal PLoS Genetics. Ankylosing Spondylitis (AS) is a common form of arthritis involving chronic inflammation particularly of the spinal and pelvic joints, which causes pain, stiffness, and often disability. Affecting up to 0.5% of the population,...
Post-traumatic stress in Crohn's disease and its association with disease activityThe inflammatory bowel disorder Crohn's disease produces its own variant of post traumatic stress (PTSD), indicates research published online in Frontline Gastroenterology.PTSD creates a vicious circle by worsening the Crohn's symptoms, indicates the study.Crohn's disease is incurable and can potentially affect the entire digestive tract, producing severe pain and diarrhoea. It is particularly common in Northern...
