Latest Cryo-electron microscopy Stories
PLEASANTON, Calif., April 15, 2015 /PRNewswire-iReach/ -- For many years the lack of sub 3 A (angstrom) high-resolution structures solved by single particle cryo-electron microscopy (cryo-EM)
A new semi-automated tool called pathwalking makes it possible to generate a "first draft" model of a protein fold taken from near-atomic resolution images of between three and six angstroms (Å), said researchers at the National Center for Macromolecular Imaging in the department of biochemistry at Baylor College of Medicine.
At the Molecular Foundry, Berkeley Lab’s acclaimed nanotechnology research center, Ren has pushed his Zeiss Libra 120 Cryo-Tem microscope to resolutions never envisioned by its German manufacturers, producing detailed snapshots of individual molecules.
Since the discovery of the microscope, scientists have tried to visualize smaller and smaller structures to provide insights into the inner workings of human cells, bacteria and viruses.
UCLA researchers report in the April 30 edition of the journal Cell that they have imaged a virus structure at a resolution high enough to effectively "see" atoms, the first published instance of imaging biological complexes at such a resolution.
Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells.