Latest Cryptococcosis Stories
Fungal Protein Found to Cross Blood-brain Barrier (PRWEB) June 12, 2014 In a remarkable series of experiments on a fungus that causes cryptococcal meningitis,
Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans -- a fungus responsible for a million cases of pneumonia and meningitis every year -- are so malleable and dangerous.
Tamoxifen, a drug currently used to treat breast cancer, also kills a fungus that causes a deadly brain infection in immunocompromised patients.
HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease.
The most cost-effective treatment for cryptococcal meningitis (a serious infection of the brain membranes, usually in people with AIDS or other immune system deficiencies) is different to that currently recommended by the World Health Organization (WHO), warranting a review of policy.
New research conducted by biologists at Texas A&M University suggests that ZOLOFT®, one of the most widely prescribed antidepressants in the world, also packs a potential preventative bonus — potent mechanisms capable of inhibiting deadly fungal infections.
Most AIDS patients, when diagnosed with a fungal infection known simply as cryptococcosis, are assumed to have an infection with Cryptococcus neoformans, but a recent study from Duke University Medical Center suggests that a sibling species, Cryptococcus gattii, is a more common cause than was previously known.
New research has shed light on the origins of a fungal infection which is one of the major causes of death from AIDS-related illnesses.
A study in this week's PLoS Medicine suggests that AIDS patients with cryptococcal meningitis who start HIV therapy are predisposed to immune reconstitution inflammatory syndrome (IRIS) â€” an exaggerated inflammatory immune response that kills up to one-third of affected people â€” if they have biomarkers (biochemicals) in their blood showing evidence of a damaged immune system that is not capable of clearing the fungal infection.