Quantcast

Latest Cryptococcus neoformans Stories

2014-06-12 23:02:20

Fungal Protein Found to Cross Blood-brain Barrier (PRWEB) June 12, 2014 In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain. The discovery — published online June 3 in mBio, the open-access, peer-reviewed journal of the American...

2013-08-27 12:35:20

HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology. Cryptococcus neoformans is the most common cause of fungal meningitis among HIV-infected individuals. While the disease is a risk for everyone with HIV who has a very low level of CD4+ T cells, researchers have discovered that those with the gene for the...

2012-07-26 01:15:05

New research conducted by biologists at Texas A&M University suggests that ZOLOFT®, one of the most widely prescribed antidepressants in the world, also packs a potential preventative bonus – potent mechanisms capable of inhibiting deadly fungal infections. The findings are the result of a two-year investigation by Xiaorong Lin, assistant professor of biology, and Matthew S. Sachs, professor of biology, involving sertraline hydrocholoride (ZOLOFT) and its effects on...

2011-05-03 13:43:41

New research has shed light on the origins of a fungal infection which is one of the major causes of death from AIDS-related illnesses. The study, published today in the journal PLoS Pathogens, funded by the Wellcome Trust and the BBSRC, shows how the more virulent forms of Cryptococcus neoformans evolved and spread out of Africa and into Asia. Cryptococcus neoformans is a species of often highly aggressive fungi. One particular strain of the fungus "“ known as Cryptococcus neoformas...

2011-03-02 21:39:07

New research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) has shown that nematode worms have to trade-off resistance to different diseases, gaining resistance to one microbe at the expense of becoming more vulnerable to another. This finding, published in PLoS ONE today (2 March 2011), reveals that the worms, called C. elegans, have a much more complex immune system than was previously thought and shows how important such trade-offs are across the animal...

2010-11-15 13:51:27

Pathogenic fungi have been found to protect themselves against unwanted genetic mutations during sexual reproduction, according to researchers at Duke University Medical Center. A gene-silencing pathway protects the fungal genome from mutations imposed by a partner during mating. This pathway was discovered in Cryptococcus neoformans, a fungus that commonly infects humans, causing over one million cases of lung and brain infection each year, and more than 600,000 deaths. A related species,...

2010-05-20 10:35:58

New research shows that nearly 1 in 5 cases of infection with the potentially deadly fungus Cryptococcus neoformans are caused by not one but multiple strains of the pathogen. Researchers from the Institut Pasteur and the University of Minnesota Medical School reported their findings May 19 in the inaugural issue of mBioâ“ž¢, the first online, open-access journal published by the American Society for Microbiology. "Koch's postulates are criteria establishing a...

d9c16a980e5457d3cd83cf6279896bc61
2009-06-16 07:50:00

In a study published in The Journal of Infectious Diseases, researchers from Albert Einstein College of Medicine of Yeshiva University have identified cells in blood that predict which HIV-positive individuals are most likely to develop deadly fungal meningitis, a major cause of HIV-related death. This form of meningitis affects more than 900,000 HIV-infected people globally"”most of them in sub-Saharan Africa and other areas of the world where antiretroviral therapy for HIV is not...

2009-02-05 10:09:31

U.S. scientists say they have determined how a deadly fungus microbe -- Cryptococcus neoformans -- evades the human immune system and causes disease. Albert Einstein College of Medicine researchers said their findings may help scientists develop new therapies or vaccines against fungal infections, such as those that occur in AIDS and transplant patients who must take lifelong immunosuppressive therapy. Scientists have known the capsule surrounding C. neoformans is essential to its ability to...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
Related