Quantcast

Latest Cryptococcus Stories

2014-06-12 23:02:20

Fungal Protein Found to Cross Blood-brain Barrier (PRWEB) June 12, 2014 In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain. The discovery — published online June 3 in mBio, the open-access, peer-reviewed journal of the American...

Deadly Human Pathogen Cryptococcus Fully Sequenced
2014-04-18 13:05:19

By Marla Vacek Broadfoot, Duke University Ten-year effort yields map for finding weaknesses in the fungus Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans -- a fungus responsible for a million cases of pneumonia and meningitis every year -- are so malleable and dangerous. Now researchers have sequenced the...

Disease-causing Genes Easily Spread In Emerging Lethal Fungus Infection
2013-09-06 12:03:28

Wellcome Trust A rare, emerging fungal disease that is spreading throughout Canada and Northwestern USA can easily pass its deadly genes to related fungal strains within the species but less readily to more distant relatives, according to a study part-funded by the Wellcome Trust. The findings will help to understand the origins of infectious outbreaks and predict the likelihood of the disease spreading to other populations and geographical areas. Cryptococcus gattii is a type of...

2011-09-02 11:44:03

Most AIDS patients, when diagnosed with a fungal infection known simply as cryptococcosis, are assumed to have an infection with Cryptococcus neoformans, but a recent study from Duke University Medical Center suggests that a sibling species, Cryptococcus gattii, is a more common cause than was previously known. The difference between these strains could make a difference in treatment, clinical course, and outcome, said Joseph Heitman, M.D., Ph.D., senior author of the study and chair of...

2011-05-03 13:43:41

New research has shed light on the origins of a fungal infection which is one of the major causes of death from AIDS-related illnesses. The study, published today in the journal PLoS Pathogens, funded by the Wellcome Trust and the BBSRC, shows how the more virulent forms of Cryptococcus neoformans evolved and spread out of Africa and into Asia. Cryptococcus neoformans is a species of often highly aggressive fungi. One particular strain of the fungus "“ known as Cryptococcus neoformas...

2010-05-20 10:35:58

New research shows that nearly 1 in 5 cases of infection with the potentially deadly fungus Cryptococcus neoformans are caused by not one but multiple strains of the pathogen. Researchers from the Institut Pasteur and the University of Minnesota Medical School reported their findings May 19 in the inaugural issue of mBioâ“ž¢, the first online, open-access journal published by the American Society for Microbiology. "Koch's postulates are criteria establishing a...

e0cfc30a8a3d70567abfedb501e2388e1
2010-05-05 10:10:00

Calgary doctors research how to minimize complications from the disease Cryptococcus disease is a rare but serious infection resulting from inhaling a toxic fungus often found in fir trees. Approximately 250 people have been infected with the disease in British Columbia since its emergence in 1999. The disease can cause meningitis, pneumonia and in 10 per cent of cases it can lead to death. Little is known about how the fungus leaves the bloodstream and enters the brain; however, researchers...

4886f3930e0b69e4cd14eff6a8df17d71
2010-04-23 06:15:00

Researchers reported Thursday that a possibly deadly fungus is spreading among people and animals throughout the northwestern United States and parts of western Canada. According to researchers, Cryptococcus gattii usually only infects people with compromised immune systems, such as persons with AIDS and those who have had transplants, but they say the new strain is genetically different. C. gattii is "worrisome because it appears to be a threat to otherwise healthy people," said Edmond...

cda1005f261f5ba111d7150b6fb23b49
2010-04-06 07:05:00

Highly dangerous Cryptococcus fungi love sugar and will consume it anywhere because it helps them reproduce. In particular, they thrive on a sugar called inositol which is abundant in the human brain and spinal cord. To borrow inositol from a person's brain, the fungi have an expanded set of genes that encode for sugar transporter molecules. While a typical fungus has just two such genes, Cryptococcus have almost a dozen, according to Joseph Heitman, M.D., Ph.D., chairman of the Duke...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
Related