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Latest Cushing's syndrome Stories

2008-08-30 09:00:21

By Asa, Sylvia L * Context.-The sellar region is the site of frequent pathology. The pituitary is affected by a large number of pathologic entities arising from the gland itself and from adjacent anatomical structures including brain, blood vessels, nerves, and meninges. The surgical pathology of this area requires the accurate characterization of primary adenohypophysial tumors, craniopharyngiomas, neurologic neoplasms, germ cell tumors, hematologic malignancies, and metastases as well as...

2008-08-30 09:00:20

By McNicol, Anne Marie * Context.-In surgical pathology practice adrenal cortical tumors are rare. However, in autopsy series adrenal cortical nodules are found frequently. These are now being identified more commonly in life when the abdomen is scanned for other disease. It is important to differentiate between benign and malignant lesions as adrenal cortical carcinoma is an aggressive tumor. Molecular genetic investigations are providing new information on both pathogenesis of adrenal...

2008-08-29 03:00:19

By Zaydfudim, Victor Stover, Daniel G; Caro, Susan W; Phay, John E Although medullary thyroid cancer (MTC) can produce adrenocorticotropic hormone (ACTH) in up to 40 per cent of cases as determined by immunohistochemistry, clinical hypercortisolism is rarely seen. We report a medullary endocrine neoplasia 2A (MEN 2A) kindred whose proband case presented with Cushing's syndrome (CS). This 51-year-old woman presented with debilitating weakness, exertional dyspnea, 50 pound weight gain, moon...

2008-08-13 18:00:12

Corcept Therapeutics Incorporated (NASDAQ: CORT) today reported financial results for the second quarter ended June 30, 2008. For the second quarter of 2008, Corcept reported a net loss of $4.4 million, or $0.09 per share, compared to a net loss of $1.4 million, or $0.04 per share, for the second quarter of 2007. For the first six months of 2008, the company reported a net loss of $8.3 million, or $0.19 per share, compared to a net loss of $4.0 million, or $0.13 per share, for the same...

2008-02-13 03:00:13

By Timonera, Elizabeth R Paiva, Maria Emilia; Lopes, Jose Manuel; Eloy, Catarina; van der Kwast, Theodore; Asa, Sylvia L Adenomatoid tumor and myelolipoma are benign, hormonally inactive tumors that are often incidental findings in the adrenal glands. Myelolipoma is more common than adenomatoid tumor in this location but both are rare, and as yet, the pathogenesis of both remains unclear.We report 2 cases of composite adenomatoid tumor and myelolipo-ma, incidentally found in the adrenal...

2007-06-14 06:07:57

By de Groot, Pieter C M van Kamp, Inge L; Zweers, Evert J K; de Kroon, Cor D; van Wijngaarden, Willem J Abstract A 28-year-old primigravida with severe oligohydramnios and pre-eclamptic symptoms was found to have Cushing's syndrome caused by an adrenocortical tumor. After meternal therapy the amniotic volume normalised, but the fetus succumbed. As clinical features of pre-eclampsia and Cushing's syndrome may overlap, diagnosis can be delayed or even missed. Keywords: Cushing's syndrome,...

2006-02-17 14:41:07

By Clementine Wallace NEW YORK (Reuters Health) - It is simplistic to suggest that lowering cortisol levels will promote weight loss, as some television ads claim, according to researchers at the Oregon Health and Science University in Portland. In their study, published in the Journal of Clinical Investigation, the scientists show that the hormone isn't the major factor involved in weight gain and fat distribution, and might actually come into play at a secondary level. "There's no...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.