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Latest Cutaneous leishmaniasis Stories

2012-01-09 19:58:11

New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself. Historically, medications for infectious diseases have been designed to kill the offending pathogen. This new strategy is important, researchers say, because many parasites and bacteria can eventually mutate their way around drugs that target them, resulting in drug resistance. In this study, scientists showed that using an experimental...

2011-10-28 12:11:35

Parasite genomes speak of evolution by changes in gene, region and chromosome number, not by mutation in genes Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level. First, they found that the DNA sequence of individual strains of each species populations is almost completely identical. It appears that only a small number of genes may cause...

2011-09-23 11:57:27

East Africa is fighting the worst kala azar outbreak in a decade. Collaboration across the region through the Leishmaniasis East Africa Platform (LEAP) has resulted in the development of a new combination therapy (SSG&PM) which is cheaper and nearly halves the length of treatment from a 30 day course of injections to 17 days. East African endemic countries are taking the necessary regulatory measures to use it in their programs, but experts warn that without international funding or...

2011-08-31 19:56:21

New research published in the Journal of Leukocyte Biology suggests that salivary components from a Leishmania vector play a relevant and direct role on neutrophils, which influence parasite burden For millions of people who live under the constant threat of Leishmania infection, a new discovery by Brazilian scientists may lead to new breakthroughs, preventing these parasites from taking hold in the body or reducing the severity of infections once they occur. In a new report appearing in...

2011-02-17 08:39:10

(Ivanhoe Newswire) "“ There's news crawling around the science world- parasitic skin infections can be treated with heat therapy and this therapy could become the first-line treatment for these infections. Parasitic skin infections are commonly seen in tropical and subtropical regions, and currently the first-line treatment is a complex drug regimen. Researchers successfully treated the skin infection in two patients whose immune systems were deficient, which lowered their bodies'...

2011-02-11 13:28:26

Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world. The researchers successfully treated the skin infection with heat therapy in two patients whose immune systems were deficient, which lowered their bodies' ability to respond to medication. Both patients have remained free of the parasitic disease, called cutaneous leishmaniasis, for more than...

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2011-02-11 08:25:00

By Michael C. Purdy, Washington University in St. Louis A parasite and a virus may be teaming up in a way that increases the parasite's ability to harm humans, scientists at the University of Lausanne in Switzerland and Washington University School of Medicine in St. Louis report this week in Science. When the parasite Leishmania infects a human, immune system cells known as macrophages respond. However, some Leishmania strains are infected with a virus that can trigger a severe response in...

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2010-07-18 07:38:58

A parasite estimated to afflict as many as 12 million people worldwide relies on a family of genes that should make it vulnerable to compounds developed to treat cancer and other disorders, researchers at Washington University School of Medicine in St. Louis have found. Scientists searched the genome of the parasite Leishmania to determine that it has three kinds of TOR kinases, proteins that are linked to cell growth and cancer and have been longstanding targets for drug development. When...

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2010-04-06 14:40:00

In the first survey of sand flies in Panama to use genetic barcoding, scientists at the Smithsonian Tropical Research Institute and Gorgas Memorial Laboratories identified 20 sand fly species from Barro Colorado Island. Two species carried Leishmania naiffi, a parasite that causes cutaneous leishmaniasis: persistent, itchy skin lesions. Three species carried Wolbachia, a bacterial parasite of insects that could contribute to a strategy to control the flies and limit disease transmission. "We...

2010-03-26 14:29:00

BRISTOL, Tenn., March 26 /PRNewswire/ -- Graceway® Pharmaceuticals announced today that the Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for Zyclara(TM), determining it to be safe and effective for the treatment of clinically typical, visible or palpable actinic keratoses (AK). The new treatment can be used on large areas of skin, including the full face or balding scalp on a convenient, 6-week dosing cycle. Zyclara shares the same...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.