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Latest Cyclin Stories

2014-04-18 15:52:50

Finding could influence cancer care and regenerative medicine An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and...

2013-11-29 14:40:55

Cyclin D1 controls cell cycle progression and microRNA biogenesis through Dicer -- a new mechanism promoting breast cancer Cyclin D1, a protein that helps push a replicating cell through the cell cycle also mediates the processing and generation of mature microRNA (miRNA), according to new research publishing November 29 in Nature Communications. The research suggests that a protein strongly implicated in human cancer also governs the non-protein-coding genome. The non-coding genome,...

2013-09-09 20:31:55

University of Montreal, McGill researchers develop new method to link signaling molecules to target regulators of cell division A team of University of Montreal and McGill University researchers have devised a method to identify how signaling molecules orchestrate the sequential steps in cell division. In an article published online today in the Proceedings of the National Academy of Sciences, the scientists explain how they could track the relationship between signaling molecules and...

2013-05-24 13:54:15

University of Montreal researchers have discovered a novel molecular mechanism that can potentially slow the progression of some cancers and other diseases of abnormal growth. In the May 23 edition of the prestigious journal Cell, scientists from the University of Montreal explain how they found that the anti-cancer and anti-proliferative drug rapamycin slows down or prevents cells from dividing. “Cells normally monitor the availability of nutrients and will slow down or accelerate...

2013-04-25 20:25:22

Mount Sinai researchers identify new targets that cause abnormal cell division Blocking certain enzymes in the cell may prevent cancer cell division and growth, according to new findings from researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai. The discovery is published in the April 25, 2013 issue of the journal Molecular Cell. In order to divide, a cell needs to create copies of its genetic material to provide to the new cells,...

2011-09-22 21:31:53

Finding could be relevant to Alzheimer's disease treatment Scientists at Dana-Farber Cancer Institute and Harvard Medical School have found that a common cancer protein leads a second, totally different life in normal adult brain cells: It helps regulates memory formation and may be implicated in Alzheimer's disease. Cyclin E is a well-known culprit that drives many types of solid tumors and blood cancers. The report, published online in Developmental Cell, is the first revelation that...

2011-08-11 10:01:00

AMSTERDAM, Aug. 11, 2011 /PRNewswire/ -- Envipco Holding N.V., a public-listed company on the Brussels Euronext NYSE "ENV" and a global provider of recycling systems and solutions to the beverage and retail industries, announces the first commercial order of its innovative compactor technology. Envipco Automaten GmbH, a subsidiary of Envipco Holding N.V., today received an order from a major German retail group for 500 compactors based on new breakthrough innovative technology. The Envipco...

2011-06-09 23:33:23

Blocking cyclin D1 might help sensitize tumors to radiation Scientists at Dana-Farber Cancer Institute have uncovered a new role for a key cancer protein, a finding that could pave the way for more-effective radiation treatment of a variety of tumors. Many cancers are driven in part by elevated levels of cyclin D1, which allow the cells to escape growth controls and proliferate abnormally. In the new research, reported in the June 9 issue of Nature, researchers discovered that cyclin D1 also...

2010-07-28 14:34:57

With a single stimulatory molecule, human insulin-producing beta cell replication can be sustained for at least four weeks in a mouse model of diabetes, according to researchers at the University of Pittsburgh School of Medicine in Diabetes, a journal of the American Diabetes Association. They also found several cocktails of molecules that drive human beta cells to replicate, as well as important differences between mouse and human beta cells that could influence how these approaches are best...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'