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Latest Cyclooxygenase Stories

2014-04-03 12:28:34

MUMBAI, India, April 3, 2014 /PRNewswire/ -- - GRC 27864 is a potent, selective, orally bioavailable inhibitor of mPGES-1 - The molecule has successfully completed pre-clinical and Phase 1 enabling studies. Regulatory submission has been filed for Phase 1 trial (first-in-human) with MHRA, UK - mPGES-1 inhibitors selectively block the production of PGE2 while sparing other prostanoids of physiological importance...

2013-10-22 23:30:40

Dr. J G Moellendorf, DC, ND, LCP discusses a recent research study reporting on the relationship between common pain killers and heart attacks, strokes, and ulcers in the stomach and small intestine, along with other side effects. He also discusses recent research into a natural alternative derived from fish. Sturgeon Bay, WI (PRWEB) October 22, 2013 Many patients consult Sturgeon Bay, Wisconsin Chiropractor and Naturopath Dr. J G Moellendorf, DC, ND, LCP looking for non-drug and...

Continued Use Of Some Painkillers Can Raise Heart Risks
2013-05-30 11:48:18

Michael Harper for redOrbit.com — Your Universe Online A new study conducted by researchers at the University of Oxford has found that common painkillers can slightly increase the risk of heart problems in the long run. Common medications, such as ibuprofen and diclofenac were specifically noted in the study as being “equally dangerous” as Vioxx, a drug which has been removed from the market in the US due to its potentially dangerous effects. The Oxford researchers...

2013-02-13 11:28:50

Diclofenac most commonly used non-steroidal anti-inflammatory drug in 15 countries, listed on 74 national drug lists, despite cardiovascular risks A study in this week's PLOS Medicine finds that the painkiller diclofenac (a non-steroidal anti-inflammatory drug (NSAID) in the same class as aspirin) is the most commonly used NSAID in the 15 countries studied and is included in the essential medicines lists of 74 low-, middle- and high-income countries, despite its known tendency to cause...

2012-05-02 21:20:19

After nearly 13 years of study and intense debate, a pair of new papers from the Perelman School of Medicine, at the University of Pennsylvania have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking it. It has been almost eight years since Vioxx® was withdrawn by Merck from the market, provoking an intense controversy about the role inhibitors of the enzyme COX-2 play in causing heart attacks and strokes. Since then,...

2012-02-14 14:09:35

Scientists at Emory University School of Medicine have identified a new group of compounds that may protect brain cells from inflammation linked to seizures and neurodegenerative diseases. The compounds block signals from EP2, one of the four receptors for prostaglandin E2, which is a hormone involved in processes such as fever, childbirth, digestion and blood pressure regulation. Chemicals that could selectively block EP2 were not previously available. In animals, the EP2 blockers could...

2011-09-28 05:53:08

(Ivanhoe Newswire) — An updated study gives new information on the cardiovascular risks of non-steroidal anti-inflammatory drugs (NSAIDs) and suggests that naproxen, a commonly used drug, and low dose ibuprofen are least likely to increase cardiovascular risks. In addition, diclofenac, even doses available without prescription, elevates the risk. Using only observational studies, because randomized controlled trials have only reported small numbers of cardiovascular events, the...

36282_web
2011-09-25 15:24:40

Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) — the subjects of years of study — still have some secrets to reveal about how they work. Vanderbilt University investigators have discovered surprising new insights into the actions of NSAIDs. Their findings, reported Sept. 25 in Nature Chemical Biology, raise the possibility of developing a new class of inflammation- and pain-fighting medicines. NSAIDs block the activity of the cyclooxygenase...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.