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Latest CYP2C19 Stories

2014-06-19 10:12:13

Washington University in St. Louis Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack. These variants increased patients’ risk of dying in the year following a first heart attack, but they appeared to do so for different reasons depending on race, according to a study at Washington University...

2014-03-18 23:33:25

Rapid CYP2C19 Testing for Personalized Antiplatelet Therapy in 600-Patient Clinical Trial with Spartan Bioscience (PRWEB) March 18, 2014 Spartan Bioscience today announced the start of a 600-patient study of personalized medicine for cardiac stent patients in Germany. The study is part of a larger clinical trial entitled “Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes Trial (TROPICAL-ACS)”. TROPICAL-ACS, led by principal...

2014-03-05 23:30:09

Dr. Dominick Angiolillo begins clinical study of rapid CYP2C19 genotyping in Jacksonville. Ottawa, Ontario (PRWEB) March 05, 2014 Spartan Bioscience today announced the start of a study of personalized medicine at the University of Florida. The Spartan RX CYP2C19 System is being used to test heart attack patients receiving cardiac stents. The study is entitled “A Pharmacodynamic Study Comparing Prasugrel Versus Ticagrelor in Patients Undergoing PCI With CYP2C19 Loss-of-function...

2013-12-12 23:28:53

Rapid CYP2C19 Testing for Heart Attack Patients Using Antiplatelet Drugs in 150-Patient Clinical Trial With Spartan Bioscience Ottawa, Ontario (PRWEB) December 12, 2013 Spartan Bioscience today announced the start of a 150-patient study of personalized medicine for cardiac stent patients in Poland, Hungary, and Lithuania. The study is sponsored by the Medical University of Warsaw, and is entitled “Bedside Genetic or Pharmacodynamic Testing to Prevent Periprocedural Myonecrosis During...

2013-11-26 23:30:44

Spartan Bioscience announces 2,000-patient clinical trial of rapid DNA testing for heart attack patients using antiplatelet drugs. Ottawa, Ontario (PRWEB) November 26, 2013 Spartan Bioscience today announced the start of a 2,000-patient study of personalized medicine for cardiac stent patients in Saudi Arabia. The study is sponsored by the University of Dammam, and is entitled “Bedside Testing of CYP2C19 Gene for Treatment of Patients with PCI with Antiplatelet Therapy.” The Spartan...

2013-11-19 23:30:33

Sample-to-result system has FDA 510(k) clearance and provides CYP2C19 test results in 60 minutes. Ottawa, Ontario (PRWEB) November 19, 2013 Spartan Bioscience today announced Clinical Technology Inc. as the distributor for its rapid CYP2C19 testing system in the eastern Midwest region of the United States. The Spartan RX CYP2C19 System provides CYP2C19 test results in less than 60 minutes from a non-invasive cheek swab. It helps doctors determine therapeutic strategies for drugs...

2012-03-29 22:16:07

Developed in Canada and conducted by researchers from the University of Ottawa Heart Institute, in partnership with Spartan Bioscience, the world's first bedside genetic test has received acknowledgment by The Lancet, the world's leading general medical journal. The article Point-of-care genetic testing for personalization of antiplatelet treatment (RAPID GENE): a prospective, randomized, proof-of-concept trial, reports on the use of a simple cheek swab test, the Spartan RX CYP2C19,...

2011-12-28 07:54:24

Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may be less responsive to the medication, a review and analysis of previous studies did not find an overall significant association between the CYP2C19 genotype and cardiovascular events, according to a study in the December 28 issue of JAMA. Clopidogrel is an antiplatelet...

2011-12-06 14:00:00

GENE-MATRIX study to determine optimal antiplatelet therapy for 4,000 cardiac stent patients Ottawa, Ontario (PRWEB) December 06, 2011 Spartan Bioscience today announced the start of GENE-MATRIXâ”the largest clinical trial to date of point-of-care DNA testing in medicine. The randomized prospective trial will enroll 4,000 patients over 2 years at up to 40 hospitals in Italy. The Spartan RX CYP2C19 point-of-care DNA testing system will be used to test heart attack patients...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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