Latest Cytochrome P450 Stories
While computer simulations of how the body metabolizes drugs save both time and money, the best results when developing new drugs come from combining such simulations with laboratory experiments.
New research in the FASEB Journal suggests that increasing the level of the P450 protein causes the creation of molecules called EETs, which lower blood pressure.
Researchers have found that increasing certain proteins in the blood vessels of mice, relaxed the vessels, lowering the animal's blood pressure.
Providing key knowledge about drug toxicity and effectiveness
FRANKLIN LAKES, N.J., Oct. 20 /PRNewswire-FirstCall/ -- Medco Health Solutions, Inc.
TOKYO and INDIANAPOLIS, Ind., May 5 /PRNewswire-FirstCall/ -- A new substudy from 1,466 patients from the Phase III TRITON-TIMI 38 clinical trial showed that patients who took prasugrel and had a reduced function of the CYP2C19 gene did not have an increased risk of cardiovascular death, heart attack or stroke compared with those patients who had normal function.
CARLSBAD, Calif., Jan. 22 /PRNewswire/ -- AutoGenomics, a leader in providing automated molecular testing solutions announced today that its CYP450 2C19 assay was used in a study to demonstrate the value of genetic variants in dosing of the antiplatelet agent, Plavix.
Dense breast tissue contains more cells believed to give rise to breast cancer, compared to non-dense tissue, U.S. researchers said. Dr.
Osmetech, a molecular diagnostics company, has launched a new genetic test for CYP450 2C9 drug metabolism.
Osmetech plc (LSE:OMH), the international molecular diagnostics company announces the launch of a genetic test for CYP450 2C9 drug metabolism.
- Forsooth! indeed! originally a parenthetical phrase used in repeating the words of another with more or less contempt or disdain.