Quantcast

Latest Cytogenetics Stories

2011-09-27 13:19:22

New research presented today at the European Society for Pediatric Endocrinology meeting has found a genetic region, which may control testicle development in the fetus. Men have XY sex chromosomes, and the development of testes is thought to occur after upregulation of the testicular SOX9 gene pathway, in the presence of factor SRY on the Y chromosome. However, the mechanism by which this testicular SOX9 upregulation occurs has so far been unclear. In this study, Dr Jacqueline Hewitt...

2011-09-19 23:08:35

Research Disputes Established Theory on Chromosome Activity Fruit flies have been indispensible to our understanding of genetics and biological processes in all animals, including humans. Yet, despite being one of the most studied of animals, scientists are still finding the fruit fly to be capable of surprises, as evidenced by new research at the University of Rochester. The latest revelation has to do with the activity of the X chromosome in male fruit flies. It was widely accepted...

2011-09-19 05:26:08

(Ivanhoe Newswire) -- A chromosomal "catastrophe" that occurs early in development may be to blame for some cases of developmental delay or cognitive disorders, according to new research. Investigators from Baylor College of Medicine analyzed the DNA of 17 patients who were referred to their center because of unexplained developmental problems. "Four were very complex," Dr. Pengfei Liu, a graduate student at BCM, was quoted as saying. "One had 18 rearrangements in one chromosome. It was...

2011-09-15 13:05:47

Using a diversity of DNA sequencing and human genome analytic techniques, researchers led by Baylor College of Medicine have identified some cases of developmental delay or cognitive disorders associated with a sudden chromosomal catastrophe that occurred early in development, perhaps during cell division when DNA is replicated. In a report in the journal Cell, Dr. Weimin Bi, assistant professor of molecular and human genetics, Dr. James R.Lupski, vice chair of molecular and human...

2011-09-15 05:14:56

(Ivanhoe Newswire) -- A chromosomal "catastrophe" that occurs early in development may be to blame for some cases of developmental delay or cognitive disorders, according to new research. Investigators from Baylor College of Medicine analyzed the DNA of 17 patients who were referred to their center because of unexplained developmental problems. "Four were very complex," Dr. Pengfei Liu, a graduate student at BCM, was quoted as saying. "One had 18 rearrangements in one chromosome. It was...

sciencepress-082511-001
2011-08-25 10:38:22

  Why different species have dissimilar sets of chromosomes? Why the differentiated species often conserve apparently identical chromosome complements? Furthermore, why, while chromosome rearrangements can considerably change the course of species evolution, certain variation among individuals and populations of some species persists indefinitely? Such questions motivate researchers to compare chromosomes in closely related species. To understand the nature of chromosome changes in...

422d2981c94c807c0c4f3d4cb7d9e3af
2011-08-18 13:48:11

When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell's interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. The unexpected degree of trial-and-error involved in this process could explain why errors in the number of chromosomes in the egg cell are the leading cause of miscarriages and severe congenital diseases such as trisomies like Down's...

2011-08-11 21:43:30

According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug that releases stem cells from the bone marrow into the blood, is unlikely to put healthy stem cell donors at risk for later development of abnormalities involving loss or gains of chromosomes that have been linked to hematologic disorders such as myelodysplastic syndromes (MDS) and acute myeloid...

2011-08-08 06:43:56

The human genome is peppered with repeated DNA elements that can vary from a few to thousands of consecutive copies of the same sequence. During meiosis"”the cell division that produces sperm and eggs"”repetitive elements place the genome at risk for dangerous rearrangements from genome reshuffling. This recombination typically does not occur in repetitive DNA, in part because much of it is assembled into specialized heterochromatin. Other mechanisms that restrain recombination in...

2011-08-02 20:57:58

A relatively simple and inexpensive method may be used to determine whether a lung cancer patient is a candidate for crizotinib therapy, according to research published in the August issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer (IASLC). Lung cancer patients with ALK rearrangement have been found to respond well to crizotinib, an ALK inhibitor currently in clinical trials. Fluorescence in situ...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
Related