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Latest Cytogenetics Stories

2010-03-16 16:00:02

Male mice born with female sex chromosomes experience hypertension seen in postmenopausal women Washington, DC "“ Researchers at Georgetown University Medical Center (GUMC) have determined that something in female sex chromosomes appears to trigger a rise in blood pressure after the onset of menopause. This finding challenges the current belief that sex hormones are largely responsible for regulating blood pressure. Their work, reported online Monday in Hypertension, is the first of its...

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2010-03-15 08:55:00

In largest study to date, chromosomal microarray analysis picks up more abnormalities than current tests A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests. Publishing in the April issue of Pediatrics (and online March 15), the authors...

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2010-02-01 08:48:38

Cells missegregate a chromosome approximately once every hundred divisions. But don't be too alarmed: new research in the Journal of Cell Biology shows that the tumor suppressor p53 limits the growth of cells with incorrect numbers of chromosomes and prevents their progression toward cancer. The study appears online February 1. Tumor cells tend to missegregate chromosomes at a particularly high frequency (a condition known as chromosomal instability, or CIN), which is probably why they are...

2010-01-14 12:39:47

Chromosomes move faster than we first thought. Research published in BioMed Central's open access journal, Genome Biology, details new findings about the way chromosomes move around the nucleus when leaving the proliferative stage of the cell cycle and entering quiescence "“ and the unexpected speed at which they move. Researchers from Brunel University's Institute for Cancer Genetics and Pharmacogenomics have been trying to understand how human chromosomes occupy different territories...

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2010-01-14 11:02:50

Contrary to a widely held scientific theory that the mammalian Y chromosome is slowly decaying or stagnating, new evidence suggests that in fact the Y is actually evolving quite rapidly through continuous, wholesale renovation. By conducting the first comprehensive interspecies comparison of Y chromosomes, Whitehead Institute researchers have found considerable differences in the genetic sequences of the human and chimpanzee Ys"”an indication that these chromosomes have evolved more...

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2009-12-10 14:01:35

EMBL scientists uncover the gene responsible for keeping females female Is it a boy or a girl? Expecting parents may be accustomed to this question, but contrary to what they may think, the answer doesn't depend solely on their child's sex chromosomes. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and the Medical Research Council's National Institute for Medical Research (NIMR) at Mill Hill, UK discovered that if a specific gene located on a non-sex...

2009-12-10 12:53:49

Researchers have discovered a new explanation for differences in the severity of mental illness in males. The more excess copies of a certain gene, the more serious the handicap. The genetic defect is situated on the X-chromosome; and it is suspected that it is the amount of copies of the GDI1 gene that is responsible. The results are being published in the American Journal of Human Genetics, and are the result of work by the group of Guy Froyen connected to VIB, a life sciences research...

2009-12-07 18:49:44

Animal study demonstrates how whole chromosome changes cause cancer Mayo Clinic researchers have proven the longstanding theory that changes in the number of whole chromosomes -- called aneuploidy -- can cause cancer by eliminating tumor suppressor genes. Their findings, which appear in the current issue of the journal Cancer Cell along with an independent commentary on the discovery, end a major controversy in the field of cancer research as to whether aneuploidy is a cause or a consequence...

2009-11-18 15:49:22

A study by neuroscientist William C. Mobley, MD, PhD, chair of the Department of Neurosciences at the University of California, San Diego School of Medicine, and colleagues at Stanford University Medical School has demonstrated a possible new approach to slowing the inevitable progression of cognitive decline found in Down\'s syndrome. The study, published in Science Translational Medicine on November 18, revealed two important new findings about Down\'s syndrome in a mouse model: 1) there is...

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2009-11-14 07:49:18

Meiosis "“ the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell "“ is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely choreographs these chromosomal interactions is a long-standing question. New findings by University of California, Berkeley, scientists show that the cell's cytoskeleton, which moves things around in the cell, plays a critical role, essentially reaching into the nucleus to...


Word of the Day
ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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