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Latest Cytogenetics Stories

2009-12-07 18:49:44

Animal study demonstrates how whole chromosome changes cause cancer Mayo Clinic researchers have proven the longstanding theory that changes in the number of whole chromosomes -- called aneuploidy -- can cause cancer by eliminating tumor suppressor genes. Their findings, which appear in the current issue of the journal Cancer Cell along with an independent commentary on the discovery, end a major controversy in the field of cancer research as to whether aneuploidy is a cause or a consequence...

2009-11-18 15:49:22

A study by neuroscientist William C. Mobley, MD, PhD, chair of the Department of Neurosciences at the University of California, San Diego School of Medicine, and colleagues at Stanford University Medical School has demonstrated a possible new approach to slowing the inevitable progression of cognitive decline found in Down\'s syndrome. The study, published in Science Translational Medicine on November 18, revealed two important new findings about Down\'s syndrome in a mouse model: 1) there is...

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2009-11-14 07:49:18

Meiosis "“ the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell "“ is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely choreographs these chromosomal interactions is a long-standing question. New findings by University of California, Berkeley, scientists show that the cell's cytoskeleton, which moves things around in the cell, plays a critical role, essentially reaching into the nucleus to...

2009-11-11 07:00:00

INDIANAPOLIS and CHICAGO, Nov. 11 /PRNewswire/ -- Dow AgroSciences LLC, a wholly owned subsidiary of The Dow Chemical Company (NYSE: DOW), and Chromatin Inc. announced today that the companies have entered into two agreements: the first provides Dow with rights to Chromatin's Mini-Chromosome technology and the second establishes an exclusive research and license agreement to combine EXZACT(TM) Precision Technology with Mini-Chromosomes, creating a novel technology platform for the...

2009-11-09 06:00:00

BEIJING, Nov. 9 /PRNewswire-Asia-FirstCall/ -- China Medical Technologies, Inc. (the "Company") (Nasdaq: CMED), a leading China-based medical device company that develops, manufactures and markets advanced in-vitro diagnostic products, today announced that the Company has received approval for its Leukemia BCR/ABL fusion gene detection FISH Probe (the "Leukemia BCR/ABL FISH Probe") from the State Food and Drug Administration of China (the "SFDA"). The Leukemia BCR/ABL FISH Probe is a...

2009-10-27 12:47:34

Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve. When two populations of a species become geographically isolated from each other, their genes diverge from one another over time. Eventually, when a male from one group mates with a female from the other group, the offspring will die or be born sterile, as crosses between horses and donkeys produce sterile mules....

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2009-09-20 08:50:00

Men that suffer from a rare disease where they are plagued with extra female genes can still produce children after having surgery that gathers their sperm, says a new study. Men with Klinefelter's syndrome have an extra X chromosome. Usually men have a single X and Y-chromosome, and women have two X chromosomes. Men with Klinefelter's syndrome have two X and one Y chromosome, which can affect their fertility. Dr. Ranjith Ramasamy at New York-Presbyterian Hospital employed a surgery that...

2009-09-17 09:17:52

A Florida State University scientist says he's found the cause of chromosomal birth defects, such as Down, XYY, Edwards, Patau and Turner's syndromes. Using yeast genetics, Assistant Professor Hong-Guo Yu and colleagues selectively removed a single protein from the cell division process called meiosis and found that when the protein known as Pds5 is missing, chromosomes fail to segregate and pair up properly, and birth defects can result. Researchers said the study shines new light on the...

2009-09-16 15:04:06

Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular player known as Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth defects such as Down syndrome can result. That discovery is groundbreaking, but so, too, is what principal investigator Hong-Guo Yu calls the "genetics trick" performed by his research team...

2009-09-14 15:41:39

New insights gained into how polyploidy and genomic change can lead to evolutionary change and plants' fitness and vigor An individual with Down syndrome and a male calico cat have one thing in common"”each has an extra chromosome. For animals, most instances of an extra chromosome result in birth defects or even death, but plants are another matter entirely. Many plants are able to survive the presence of an extra copy of their entire genome (known as polyploidy) and are often even...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.