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Latest Cytoskeleton Stories

Researchers Help Develop A Dynamic Model Of Tissue Failure
2013-12-12 17:45:57

University of Pennsylvania The idea of growing replacement tissue to repair an organ, or to swap it out for an entirely new one, is rapidly transitioning from science fiction to fact. Tissue engineering techniques are improving in their ability to generate three-dimensional masses of cells and provide them with vascular systems for keeping them alive, but a more mathematically rigorous approach for designing these tissues is still needed. Researchers at the University of Pennsylvania,...

2013-11-29 00:20:06

Tokyo, Nov 29, 2013 - (ACN Newswire) - Researchers at Waseda University in Japan have identified key information to help explain the formation of the "spindle apparatus", a structure required for cell division. Their findings shed light on the mechanisms behind "self-organization" - an essential characteristic of biological structures.Organisms are composed of a variety of structures including muscles, internal organs, and brains, all of which are created through a process known as...

2013-11-25 04:20:04

Tokyo, Nov 25, 2013 - (ACN Newswire) - Researchers at Waseda University in Japan have for the first time directly observed the "molecular motor", called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes during cell division. Their findings are expected to contribute greatly to elucidating the molecular mechanisms of chromosome segregation, a key aspect of the development of certain medical disorders including cancer and birth defects.A human being begins as...

2013-10-21 13:32:23

Clarified role of signal-relay proteins may help explain spread of cancer Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell. It was already known that in directional movement, the network is activated by sensor proteins on the...

Molecular Muscles Inside Cells Help Them Sense, Respond To Their Environments
2013-10-21 07:27:59

Johns Hopkins Medicine Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities. A summary of the discovery, published online Oct. 20 in the journal Nature Materials, specifically sheds light on how forces outside of cells are translated into internal signals. A computer model the researchers...

2013-07-29 16:33:05

Crystal structure of a key initiation protein while bound is captured in one of two newly reported studies University of Oregon biochemists have determined how tiny synthetic molecules disrupt an important actin-related molecular machine in cells in one study and, in a second one, the crystal structure of that machine when bound to a natural inhibitor. The accomplishments -- done in the name of fundamental understanding, or basic science -- provide new windows on the complexities of...

New Research Challenges 50 Years Of Muscle Knowledge
2013-07-10 10:54:49

Michael Harper for redOrbit.com - Your Universe Online For the past 50 years, scientists and health professionals have operated with the knowledge that biceps are packed with long ropes of filaments. When the bicep is used to lift a heavy object or flex, these filaments were understood to shorten or contract the muscle and give it its power. A new study from the University of Washington (UW) challenges this notion, saying that while the general idea of filaments contracting is the same,...

2013-06-27 12:39:52

Scientists at the University of East Anglia have made a major advancement in understanding tissue development that has important implications for cancer. Findings published today in the Journal of Cell Science show how the protein EB2 is a key regulator of tube-like structures inside cells and critical for normal tissue development and function. The findings are an important step in the race to find cures for cancers including gut, breast and pancreatic cancer. Microtubules are...

Promise In Duchenne Muscular Dystrophy Shown With Genetic Editing
2013-06-05 08:48:09

Duke University Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular dystrophy, in cell samples from Duchenne patients. Instead of the common gene therapy approach of adding new genetic material to "override" the faulty gene, the Duke scientists have developed a way to change the existing mutated gene responsible for the disorder into a normally...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'