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Latest Cytoskeleton Stories

2012-02-03 12:06:30

Small molecules at the cell's membrane enable cell movement Cell biologists at Johns Hopkins have identified key steps in how certain molecules alter a cell´s skeletal shape and drive the cell´s movement. Results of their research, published in the December 13 issue of Science Signaling, have implications for figuring out what triggers the metastatic spread of cancer cells and wound-healing. “Essentially we are figuring out how cells crawl,” says Takanari Inoue,...

2012-01-30 12:36:51

A new study in the Journal of General Physiology (www.jgp.org) uses state-of-the-art fluorescence microscopy to provide a striking 3-D picture of how class V myosins (myoV) "walk" along their actin track. The myosin superfamily of mechanoenzymes, more commonly referred to as molecular motors, play an important role in muscle contraction and other basic cellular processes. MyoV, one of the most highly studied molecular motors, has the ability to travel long distances by taking multiple...

2012-01-17 22:38:41

New research explains how cells regulate their bonds during the development of new blood vessels. For the first time, the role of the protein Raf-1 in determining the strength of the bond between cells has been shown. If Raf-1 is not present, the cells cannot stick together and the formation of new blood vessels is inhibited. This discovery may one day lead to new approaches to cancer treatment. Angiogenic sprouting, the process by which new blood vessels grow from existing vessels, is a...

Perfect Micro Rings Woven From Muscle Fibers
2011-11-16 03:39:27

[ Watch the Video ] A biological model system that dead-ends in an 'absorbing state' Supplied with sufficient energy, a freight train would ride the rails as far as they go. But nature also knows systems whose dynamics suddenly turn into a kind of endless loop. Like in a hamster wheel, a train caught up in such a system would continue running, but without moving forward. Scientists from the Cluster of Excellence Nanosystems Initiative Munich have now succeeded in building a simple model...

2011-11-07 16:43:52

How a molecular traffic jam impacts cell division Interdisciplinary research between biology and physics aims to understand the cell and how it organizes internally. The mechanisms inside the cell are very complicated. LMU biophysicist Professor Erwin Frey, who is also a member of the Cluster of Excellence “Nanosystems Initiative Munich” (NIM) is working with his group on one particular issue involved in the cell´s life. The professor for statistical and biological physics...

Cells Are Crawling All Over Our Bodies
2011-10-19 03:28:51

Biologists at Florida State devise new way to watch how cells move For better and for worse, human health depends on a cell's motility —— the ability to crawl from place to place. In every human body, millions of cells —are crawling around doing mostly good deeds ——— though if any of those crawlers are cancerous, watch out. "This is not some horrible sci-fi movie come true but, instead, normal cells carrying out their daily duties," said Florida State...

2011-09-15 20:27:25

Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, dubbed "UNC-45A," was also determined to be more active in breast cancer cells than in normal breast cells. University of Texas Medical Branch at Galveston scientists describe these findings and others in a paper now online in the Journal of Molecular Biology. "As a...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.