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Latest Cytoskeleton Stories

2010-12-10 13:40:03

For years, scientists have tried to understand why children with Duchenne muscular dystrophy experience severe muscle wasting and eventual death. After all, laboratory mice with the same mutation that causes the disease in humans display only a slight weakness. Now research by scientists at the Stanford University School of Medicine, and a new animal model of the disease they developed, points a finger squarely at the inability of human muscle stem cells to keep up with the ongoing damage...

2010-12-07 15:36:06

Researchers at the University of Georgia have discovered a central switch that controls whether cells move or remain stationary. The misregulation of this switch may play a role in the increased movement of tumor cells and in the aggressiveness of tumors themselves. "Malignant cancer arises when cancer cells acquire the ability to move away from their primary tissue location," said Natalia Starostina assistant research scientist in the UGA department of cellular biology and lead author of the...

2010-11-22 19:17:18

A new study reveals that muscle cells fuse together during development by poking "fingers" into each other to help break down the membranes separating them. The study appears online on November 22, 2010 in the Journal of Cell Biology(www.jcb.org). During muscle development, individual muscle cells fuse together to form long myotubes containing multiple cell nuclei. In the fruit fly Drosophila melanogaster, fusion occurs between two different types of muscle cell: founder cells and...

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2010-11-15 10:45:14

University of Maryland researchers studied test that detects low levels of troponin T Researchers at the University of Maryland School of Medicine in Baltimore report that a new, highly sensitive investigative blood test may help predict the risk of heart failure and cardiovascular death much earlier than previously possible in older people who do not have symptoms of heart failure. Results of a study were presented at the Scientific Sessions of the American Heart Association on November 15,...

2010-11-07 10:49:50

Potentially big implications for cancer control By tracking the flow of information in a cell preparing to split, Johns Hopkins scientists have identified a protein mechanism that coordinates and regulates the dynamics of shape change necessary for division of a single cell into two daughter cells. The protein, called 14-3-3, sits at an intersection where it integrates converging signals from within the cell and cues cell shape change and, ultimately, the splitting that allows for normal and...

2010-11-04 10:03:00

MISSISSAUGA, Ontario, Nov. 4, 2010 /PRNewswire/ -- CardioGenics Holdings Inc. (OTC Bulletin Board: CGNH) announced today that it has completed a private placement under which it has raised $1,930,575. The shares issued in connection with the private placement do not have registration rights and are, therefore, subject to the rights and restrictions of Rule 144. Further, no warrants were issued in connection with the private placement. The funding provides the Company with sufficient...

2010-10-15 16:32:31

Researchers at the University of Minnesota Medical School have gained insight into how different types of age-related hearing loss may occur in humans. The discovery could eventually help physicians develop drugs to combat progressive hearing loss. Their paper is published on October 14 in the open-access journal PLoS Genetics. James Ervasti, Ph.D., and colleague Ben Perrin, Ph.D., studied how two very closely related genes contribute to hearing function in mice. Mutations in the same genes...

2010-10-15 07:00:00

SOUTH PLAINFIELD, N.J., Oct. 15 /PRNewswire/ -- PTC Therapeutics, Inc. today announced that final analyses of Phase 2b efficacy data suggest the investigational new drug ataluren slowed the loss of walking ability in patients with nonsense mutation dystrophinopathy, a disease continuum comprising Duchenne and Becker muscular dystrophy (nmDBMD). These data were presented at the International Congress of the World Muscle Society in Kumamoto, Japan and will be the basis of interactions...

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2010-10-15 08:16:31

Unless you are in a field of study related to cell biology, you most likely have never heard of Ndc80. Yet this protein complex is essential to mitosis, the process by which a living cell separates its chromosomes and distributes them equally between its two daughter cells. Now, through a combination of cryo-electron microscopy and three-dimensional image reconstruction, a team of researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC)...

2010-10-11 14:30:52

Researchers at the Carnegie Institution for Science, with colleagues at the Nara Institute of Science and Technology, observed for the first time a fundamental process of cellular organization in living plant cells: the birth of microtubules by studying recruitment and activity of individual protein complexes that create the cellular protein network known as the microtubule cytoskeleton"”the scaffolding that provides structure and ultimately form and shape to the cell. These fundamental...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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