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Latest Cytoskeleton Stories

2010-11-04 10:03:00

MISSISSAUGA, Ontario, Nov. 4, 2010 /PRNewswire/ -- CardioGenics Holdings Inc. (OTC Bulletin Board: CGNH) announced today that it has completed a private placement under which it has raised $1,930,575. The shares issued in connection with the private placement do not have registration rights and are, therefore, subject to the rights and restrictions of Rule 144. Further, no warrants were issued in connection with the private placement. The funding provides the Company with sufficient...

2010-10-15 16:32:31

Researchers at the University of Minnesota Medical School have gained insight into how different types of age-related hearing loss may occur in humans. The discovery could eventually help physicians develop drugs to combat progressive hearing loss. Their paper is published on October 14 in the open-access journal PLoS Genetics. James Ervasti, Ph.D., and colleague Ben Perrin, Ph.D., studied how two very closely related genes contribute to hearing function in mice. Mutations in the same genes...

2010-10-15 07:00:00

SOUTH PLAINFIELD, N.J., Oct. 15 /PRNewswire/ -- PTC Therapeutics, Inc. today announced that final analyses of Phase 2b efficacy data suggest the investigational new drug ataluren slowed the loss of walking ability in patients with nonsense mutation dystrophinopathy, a disease continuum comprising Duchenne and Becker muscular dystrophy (nmDBMD). These data were presented at the International Congress of the World Muscle Society in Kumamoto, Japan and will be the basis of interactions...

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2010-10-15 08:16:31

Unless you are in a field of study related to cell biology, you most likely have never heard of Ndc80. Yet this protein complex is essential to mitosis, the process by which a living cell separates its chromosomes and distributes them equally between its two daughter cells. Now, through a combination of cryo-electron microscopy and three-dimensional image reconstruction, a team of researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC)...

2010-10-11 14:30:52

Researchers at the Carnegie Institution for Science, with colleagues at the Nara Institute of Science and Technology, observed for the first time a fundamental process of cellular organization in living plant cells: the birth of microtubules by studying recruitment and activity of individual protein complexes that create the cellular protein network known as the microtubule cytoskeleton"”the scaffolding that provides structure and ultimately form and shape to the cell. These fundamental...

2010-10-08 01:58:14

Natural immunity to dystrophin may contribute to muscle disease and complicate experimental therapies An immune reaction to dystrophin, the muscle protein that is defective in patients with Duchenne muscular dystrophy, may pose a new challenge to strengthening muscles of patients with this disease, suggests a new study appearing in the October 7, 2010, issue of The New England Journal of Medicine. Duchenne muscular dystrophy (DMD) is a hereditary and lethal neuromuscular disease characterized...

2010-09-27 17:33:42

Researchers have shown that LIM kinase (LIMK), an important regulator of actin cytoskeleton dynamics, plays a key role in cancer metastasis. The study appears online on September 27 in The Journal of Cell Biology www.jcb.org. Cancer metastasis is a multi-stage process that starts with the invasion of tumor cells into their surrounding tissue. The ability of metastatic cells to invade requires reorganization of the actin-myosin cytoskeleton, which is controlled by a sophisticated network of...

2010-09-21 21:58:20

Insight may lead to better understanding of how cells respond to stress Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell. The research has implications for cancer, as well as other diseases, since alterations in the cytoskeleton are often associated with disease. The research was published...

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2010-09-09 09:10:42

A new University of Georgia study published in the journal Nature  has identified a critical enzyme that keeps traffic flowing in the right direction in the nervous system, and the finding could eventually lead to new treatments for conditions such as Alzheimer's and Parkinson's disease. "There was no medical or any other applied science drive for this project; it was purely curiosity about how transport inside cells works," said study co-author Jacek Gaertig, professor in the cellular...

2010-09-01 20:57:00

Probing for principles underlying flock patterns For the casual observer it is fascinating to watch the orderly and seemingly choreographed motion of hundreds or even thousands of fish, birds or insects. However, the formation and the manifold motion patterns of such flocks raise numerous questions fundamental to the understanding of complex systems. A team of physicists from Technische Universitaet Muenchen (TUM) and LMU Muenchen has developed a versatile biophysical model system that opens...