Quantcast

Latest Cytoskeleton Stories

2010-10-08 01:58:14

Natural immunity to dystrophin may contribute to muscle disease and complicate experimental therapies An immune reaction to dystrophin, the muscle protein that is defective in patients with Duchenne muscular dystrophy, may pose a new challenge to strengthening muscles of patients with this disease, suggests a new study appearing in the October 7, 2010, issue of The New England Journal of Medicine. Duchenne muscular dystrophy (DMD) is a hereditary and lethal neuromuscular disease characterized...

2010-09-27 17:33:42

Researchers have shown that LIM kinase (LIMK), an important regulator of actin cytoskeleton dynamics, plays a key role in cancer metastasis. The study appears online on September 27 in The Journal of Cell Biology www.jcb.org. Cancer metastasis is a multi-stage process that starts with the invasion of tumor cells into their surrounding tissue. The ability of metastatic cells to invade requires reorganization of the actin-myosin cytoskeleton, which is controlled by a sophisticated network of...

2010-09-21 21:58:20

Insight may lead to better understanding of how cells respond to stress Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell. The research has implications for cancer, as well as other diseases, since alterations in the cytoskeleton are often associated with disease. The research was published...

b7397b04554909cffbefe23b1fba209a
2010-09-09 09:10:42

A new University of Georgia study published in the journal Nature  has identified a critical enzyme that keeps traffic flowing in the right direction in the nervous system, and the finding could eventually lead to new treatments for conditions such as Alzheimer's and Parkinson's disease. "There was no medical or any other applied science drive for this project; it was purely curiosity about how transport inside cells works," said study co-author Jacek Gaertig, professor in the cellular...

2010-09-01 20:57:00

Probing for principles underlying flock patterns For the casual observer it is fascinating to watch the orderly and seemingly choreographed motion of hundreds or even thousands of fish, birds or insects. However, the formation and the manifold motion patterns of such flocks raise numerous questions fundamental to the understanding of complex systems. A team of physicists from Technische Universitaet Muenchen (TUM) and LMU Muenchen has developed a versatile biophysical model system that opens...

2010-08-26 12:57:12

Findings add new dimension to how memories are encoded, suggest new therapeutic targets Functioning much like gears in a machine, cellular motor proteins are critical to dynamic functions throughout the body, including muscle contraction, cell migration and cellular growth processes. Now, neuroscientists from UC Irvine and the Florida campus of The Scripps Research Institute report that motor proteins also play a critical role in the stabilization of long-term memories. The findings add an...

2010-08-25 14:54:23

New findings could lead to better treatments for memory disorders Scientists from the Florida campus of The Scripps Research Institute have discovered a mechanism that plays a critical role in the formation of long-term memory. The findings shed substantial new light on aspects of how memory is formed, and could lead to novel treatments for memory disorders. The study was published as the cover story of the journal Neuron on August 26, 2010. In the study, the scientists found that a main...

2010-07-13 18:16:54

Team maps targets with hopes of blocking reproduction and rendering infection down for the count In any battle, sizing up one's opponent is a critical first step. For researchers fighting a bacterial infection, that means assessing every nook and cranny of the malicious microorganism and identifying which ones to attack. At the Center for Biological Research of the Spanish Research Council in Madrid, scientists are devising maneuvers they hope will take out bacteria at their molecular knees,...

2010-07-07 15:45:15

Japanese team hopes new discovery will aid in creation of therapies for visual, hearing problems It's safe to say that cilia, the hairlike appendages jutting out from the smooth surfaces of most mammalian cells, have long been misunderstood "“ underestimated, even. Not to be confused with their whiplike cousins flagella, which propel sperm, one type of cilia has been known to serve as microscopic conveyor belts. (Picture cilia reaching up like concertgoers supporting a crowd-surfer.)...

2010-07-07 12:42:14

In this study, Shuichi Takeda at Nagoya University and colleagues present the X-ray crystal structures of the actin capping protein (CP) complexed with its inhibitors, V-1 and CARMIL, and demonstrate that the two regulators modulate the filament capping activity in very different manners. These findings will be published next week in the online, open access journal PLoS Biology. Dynamic rearrangement of actin cytoskeleton structure is fundamental to many cellular processes, such as neuronal...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.