Latest Daniel Kohane Stories

2012-08-27 19:36:41

'Cyborg' tissues could merge bioengineering with electronics for drug development, implantable therapeutics A multi-institutional research team has developed a method for embedding networks of biocompatible nanoscale wires within engineered tissues. These networks–which mark the first time that electronics and tissue have been truly merged in 3D–allow direct tissue sensing and potentially stimulation, a potential boon for development of engineered tissues that incorporate...

Image 1 - Gold Nanowires Offer Breakthrough In Cardiac Patches
2011-09-27 05:21:25

Researchers at Massachusetts Institute of Technology (MIT) and Children´s Hospital Boston have developed cardiac patches using gold nanowires, which could create parts of tissue whose cells beat in time, mimicking the way the natural heart muscle works, MIT reported on Monday. The breakthrough, which was published this week in the journal Nature Nanotechnology, could someday help those who have suffered a heart attack.   The research improves on existing cardiac patches, which...

2011-09-20 00:14:55

Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries Could engineered fatty particles help prevent AIDS? Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries HIV vaccines are in their infancy, and effective microbicides to prevent sexual transmission of HIV still don't exist. Protection is especially needed for women, who make up nearly half of all global cases. Researchers at...

2010-02-01 18:01:14

Surprise finding may have implications for labor anesthesia, orthopedics and more One of the holy grails of local anesthesia is the ability to achieve a long-lasting nerve block that eliminates pain sensation while not affecting motor function. Now, researchers at Children's Hospital Boston have discovered an anesthetic approach that seems to do just that. If it proves to work in humans as well as it did in rats, it could be useful in a variety of medical applications, providing, for example,...

2009-09-18 10:29:08

Many medical conditions, such as chronic pain, cancer and diabetes, require medications that cannot be taken orally, but must be dosed intermittently, on an as-needed basis, over a long period of time. A few delivery techniques have been developed, using an implanted heat source, an implanted electronic chip or other stimuli as an "on-off" switch to release the drugs into the body. But thus far, none of these methods can reliably do all that's needed: repeatedly turn dosing on and off,...

2009-08-05 06:45:00

According to new research, a contact lens that gradually dispenses medication to the eye might ease treatment for glaucoma and other eye ailments, assuming it advances past animal testing to human testing. People that use eye drops for conditions like glaucoma medicate their eyes several times a day, which is burdensome and inefficient.  Because of the natural blinking of the eye and tear production, only a little bit of medication is absorbed by the eye.  The authors of the study...

2009-07-21 19:10:00

Taking eye drops multiple times a day can be difficult for patients to do, and because of blinking and tearing, as little as 1 to 7 percent of the dose is actually absorbed by the eye. Now, researchers led by Daniel Kohane, MD, PhD, director of the Laboratory for Biomaterials and Drug Delivery at Children's Hospital Boston, have developed special contact lenses that can gradually dispense a constant amount of medication to the eye, at adjustable rates. They describe their prototype lens in...

Word of the Day
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.