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Latest Daniele Piomelli Stories

2012-03-06 23:06:47

UCI-led study points to role endocannabinoids play in energy metabolism Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, this can happen, at least in the lab. To create this hypermetabolic state, UCI pharmacology professor Daniele Piomelli and colleagues engineered neurons in the forebrains of mice to limit production...

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2011-07-06 05:35:00

A new study may shed light on why some people have such a hard time eating only a few potato chips or a single fry. Researchers at University of California-Irvine found that fats in these foods make them nearly irresistible, and trigger a surprising biological mechanism that likely drives our nearly insatiable appetite for more. The apparent culprits are natural, marijuana-like chemicals in the body known as endocannabinoids. In their study, researchers Daniele Piomelli, Nicholas DiPatrizio...

2011-07-05 12:21:46

UCI study helps explain why potato chips, french fries are complicit in weight gain Recent studies have revealed potato chips and french fries to be the worst contributors to weight gain "“ and with good reason. Have you ever wondered why you can't eat just one chip or a single fry? It's not just the carbohydrates at fault. UC Irvine researchers Daniele Piomelli, Nicholas DiPatrizio and colleagues found that fats in these foods make them nearly irresistible and trigger a surprising...

2010-09-20 22:35:07

Drug created by UCI, Italian team inhibits enzyme that breaks down anandamide American and Italian researchers have found that a novel drug allows anandamide "“ a marijuana-like chemical in the body "“ to effectively control pain at the site of an injury. Led by Daniele Piomelli, the Louise Turner Arnold Chair in Neurosciences and director of the Center for Drug Discovery at UC Irvine, the study suggests that such compounds could form the basis of pain medications that don't...

2010-09-10 11:53:00

Low levels of the omega-3 fatty acid may contribute to the neurodegenerative disease UC Irvine researchers have discovered that markedly depleted amounts of an omega-3 fatty acid in brain tissue samples from Alzheimer's patients may be due to the liver's inability to produce the complex fat, also contained in fish-oil supplements. Low levels of docosahexaenoic acid, or DHA, have been associated with the chronic neurodegenerative disease affecting millions of Americans, but no cause had been...

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2008-10-08 09:09:32

Results point to natural approaches for fighting obesity, eating disorders Fatty foods may not be the healthiest diet choice, but those rich in unsaturated fats "“ such as avocados, nuts and olive oil "“ have been found to play a pivotal role in sending this important message to your brain: stop eating, you're full. A new study by UC Irvine pharmacologists shows that these fats trigger production of a compound in the small intestine that curbs hunger pangs. This discovery, the...

2005-06-22 12:00:00

A new study shows, for the first time, that the release of the body's own marijuana-like compounds is crucial to stress-induced analgesia "“ the body's way of initially shielding pain after a serious injury. The work, led by scientists at the University of Georgia and the University of California, Irvine, may yield a target for new drug therapies that will completely bypass the current arguments over the use of medical marijuana. In theory, the new research makes it possible to design a...

2005-06-21 22:45:00

Irvine, Calif. - A marijuana-like chemical in the brain is responsible for suppressing pain caused by severe injury during stressful moments, according to UC Irvine researchers, and this discovery may lead to a new class of drugs with fewer side effects than those of many existing pain medications. Daniele Piomelli, professor of pharmacology and director of the Center for Drug Discovery in the UCI School of Medicine, and colleagues have found that marijuana-like chemicals called...

2004-11-26 15:00:10

SAN DIEGO - A decade ago, when Daniele Piomelli went to scientific conferences, he was often the only researcher studying cannabinoids, the class of chemicals that give marijuana users a high. His work often drew snickers and jokes - but no more. At the annual Society for Neuroscience conference this month, scientists here delivered almost 200 papers on the subject. Why the attention? Many scientists believe marijuana-like drugs might be able to treat a wide range of diseases, far beyond...


Word of the Day
negawatt
  • A unit of saved energy.
Coined by Amory Lovins, chairman of the Rocky Mountain Institute as a contraction of negative watt on the model of similar compounds like megawatt.