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Last updated on April 19, 2014 at 7:35 EDT

Latest David Lane Stories

2014-01-09 00:20:05

Source: A*STARA*STAR-led international consortium completely decodes the first shark-familymember genomeSingapore, Jan 9, 2014 - (ACN Newswire) - Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) led an international team of researchers that sequenced and analysed the genome of the elephant shark. A comparison of the elephant shark genome with human and other vertebrate genomes revealed why the skeleton of sharks consists entirely of cartilage instead of bones. The...

2013-11-08 04:20:03

This discovery could eradicate cancers more effectively and prevent relapsesSingapore, Nov 8, 2013 - (ACN Newswire) - Scientists at A*STAR have discovered an enzyme, Wip1 phosphatase, as a potential target to weed out the progression of cancer. Although studies in the past have revealed that this enzyme plays a critical role in regulating the budding of tumours, scientists have for the first time unearthed a mechanism for its mode of action.The research was conducted...

2013-08-06 04:20:03

Singapore, Aug 6, 2013 - (ACN Newswire) - A team of scientists led by Associate Professor Zeng Qi(1) from A*STAR's Institute of Molecular and Cell Biology (IMCB) have discovered a new biomarker which will help physicians predict how well cancer patients respond to cancer drugs. Having the means to identify patients who are most likely to benefit from currently available cancer drugs not only reduces substantially the healthcare cost for the patient, it could mean saving precious lives by...

2012-07-17 08:20:01

Singapore, July 17, 2012 - (ACN Newswire) - A*STAR Chief Scientist, Professor Sir David Lane is the recipient of this year's Cancer Research UK Lifetime Achievement Award. The award recognises his contribution to the pioneering research that led to the discovery of the p53, often called the 'guardian of the genome'.The p53 protein, which is mutated in more than 50 per cent of cancers, was first discovered in 1979 and since then Professor Lane has dedicated his career to understanding how it...

2010-05-24 08:48:13

Healthy cells need not be destroyed during cancer treatment Researchers from the p53 Laboratory of Singapore's Agency for Science, Technology and Research (A*STAR), have made a finding that makes feasible a unique method of cancer treatment. Their work, published online in the leading journal Cell Death and Differentiation today , offers new insight on how to tap on the properties of p53, the "Ëœguardian of the genome' , to more effectively kill cancer cells while sparing normal...

2009-10-13 14:30:12

How p53 'turns on' genes now better understood Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequences of nucleotides in the gene's DNA. Their findings provide a missing piece about p53 gene repression that has eluded researchers investigating the master regulator, which undergoes mutations or deletions in over 50 percent of all cancers. "The precise interaction of p53...

2008-10-14 18:00:13

Citizens for Pennsylvania's Future (PennFuture) today announced the election of David Lane, President of LevLane Advertising, to vice chair of its board of directors for a two-year term. Lane will work to enforce environmental laws and advocate for the transformation of public policy, public opinion and the marketplace to restore and protect the environment and safeguard public health. "I am especially excited that David Lane has been elected vice chair on our board of directors," said...