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Latest David Mangelsdorf Stories

2011-03-24 20:53:19

Researchers at UT Southwestern Medical Center have discovered a hormone pathway that potentially could lead to new ways of treating type 1 diabetes independent of insulin, long thought to be the sole regulator of carbohydrates in the liver. Results of this new study will be published March 25 in Science. Another hormone, fibroblast growth factor 19 (FGF19), has insulin-like characteristics beyond its role in bile acid synthesis. Unlike insulin, however, FGF19 does not cause excess glucose to...

2010-12-15 14:30:40

Researchers at UT Southwestern Medical Center have discovered sets of genes active in cancer cells and normal tissue that predict survival time and potential new treatments for patients with non-small cell lung cancer. "Patient responses to cancer treatment vary widely and often depend on subtle biological differences among tumors," said Dr. David Mangelsdorf, chairman of pharmacology at UT Southwestern and co-lead author of the study, published Dec. 14 by PLoS Medicine. "These findings are...

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2009-05-26 13:12:24

New findings by researchers UT Southwestern Medical Center are accelerating efforts to eradicate worm infections that afflict a third of the world's population. The new findings, available online and in an upcoming issue of the Proceedings of the National Academy of Sciences, demonstrate that a biochemical system that controls development and reproduction of Caenorhabditis elegans, a common research worm, also provides the same function in several parasitic nematodes, including hookworm. In...

2005-08-11 21:10:00

DALLAS "“ Aug. 11, 2005 "“ Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition. The metabolic syndrome, which affects more than 47 million Americans, is a constellation of disorders of the body's metabolism "“ such as abdominal obesity, hypertension and insulin...


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ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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